Varaico: Literature-Extracted Genetic Variants

Gene:A2M
Variant:p.I1000V
Back to variants list

A2M

NM_000014.6:p.I1000V

Associated Papers

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Elife, 2024

38277211 (PubMed )
Supplement: elife-89762-supp1.xlsx › Variants

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Biorxiv : the Preprint Server for Biology, 2023

37292598 (PubMed )
Supplement: media-1.xlsx › Variants

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort.

Dong L et al.

Journal of Alzheimer's Disease : Jad, 2022

34958020 (PubMed )
Supplement: jad-85-jad215067-s001.pdf

Searching for Genetic Biomarkers for Hereditary Angioedema Due to C1-Inhibitor Deficiency (C1-INH-HAE).

Parsopoulou F et al.

Frontiers in Allergy, 2022

Novel heterozygous mutation in alpha-2-macroglobulin (A2M) suppressing the binding of amyloid-β (Aβ).

Qiu G et al.

Frontiers in Neurology, 2022

Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge.

Brancaccio M et al.

Diagnostics (basel, Switzerland), 2021

34829491 (PubMed )
Supplement: diagnostics-11-02144-s001.zip › diagnostics-1421633-supplementary.xlsx › Supplementary_Table_S3

Influence of Pathogenic and Metabolic Genes on the Pharmacogenetics of Mood Disorders in Alzheimer's Disease.

Cacabelos R et al.

Pharmaceuticals (basel, Switzerland), 2021

Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease.

Blumenau S et al.

Scientific Reports, 2020

32345996 (PubMed )
Supplement: 41598_2020_63183_MOESM5_ESM.xlsx › S1

The Associations of PMF1, ICAM1, AGT, TRIM65, FBF1, and ACOX1 Variants With Leukoaraiosis in Chinese Population.

Huang WQ et al.

Frontiers in Genetics, 2019

Pharmacogenetic Study on the Impact of Rivastigmine Concerning Genetic Variants of A2M and IL-6 Genes on Iranian Alzheimer's Patients.

Zamani M et al.

Molecular Neurobiology, 2016

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.

Sassi C et al.

Plos One, 2016

27249223 (PubMed )
Supplement: pone.0150079.s002.xlsx › Tabelle1

Influence of Alpha-2-Macroglobulin 5 bp I/D and Ile1000Val polymorphisms on the susceptibility of Alzheimer's disease: a systematic review and meta-analysis of 52 studies.

Chen H et al.

Cell Biochemistry and Biophysics, 2014

Association of polymorphisms in the LRP1 and A2M genes with Alzheimer's disease in the northern Chinese Han population.

Yuan Q et al.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 2013

Recent human evolution has shaped geographical differences in susceptibility to disease.

Marigorta UM et al.

Bmc Genomics, 2011

21261943 (PubMed )
Supplement: 1471-2164-12-55-S8.XLS › Hoja1

Lack of interaction between LRP1 and A2M polymorphisms for the risk of Alzheimer disease.

Bruno E et al.

Neuroscience Letters, 2010

Meta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's disease.

Llorca J et al.

Acta Neurologica Scandinavica, 2008

Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study.

Tanskanen M et al.

Annals of Medicine, 2008

Genetics of Alzheimer's disease. A rapidly evolving field.

Serretti A et al.

Journal of Alzheimer's Disease : Jad, 2007

Genetic studies of A2M and BACE1 genes in Chinese Han Alzheimer's disease patients.

Cai L et al.

Neuroreport, 2005

[No evidence for genetic association between alpha-2 macroglobulin I1000V polymorphism and sporadic Alzheimer's disease in two independent Chinese populations].

Sun Y et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2005

Molecular genetics of late-onset Alzheimer's disease.

Kamboh MI

Annals of Human Genetics, 2004

Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease.

Styczynska M et al.

Neuroscience Letters, 2003

Genetic association of alpha2-macroglobulin polymorphisms with AD in southern Italy.

Zappia M et al.

Neurology, 2002

Alpha-2 macroglobulin I1000 V polymorphism in Chinese sporadic Alzheimer's disease and Parkinson's disease.

Tang G et al.

Neuroscience Letters, 2002

Candidate gene association studies in sporadic Alzheimer's disease.

Combarros O et al.

Dementia and Geriatric Cognitive Disorders, 2002

Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.

McIlroy SP et al.

American Journal of Medical Genetics, 2001

The genetics of late-onset Alzheimer's disease.

Myers AJ et al.

Current Opinion in Neurology, 2001

Genetic markers in the diagnosis of Alzheimer's disease.

Rogaeva E et al.

Journal of Alzheimer's Disease : Jad, 2001

Lack of association between alpha2-macroglobulin polymorphisms and Alzheimer's disease.

Wang X et al.

Human Genetics, 2001

The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis.

Koster MN et al.

Neurology, 2000

No genetic association between alpha-2 macroglobulin I1000V polymorphism and Japanese sporadic Alzheimer's disease.

Shibata N et al.

Neuroscience Letters, 2000

Semiautomated PCR-single-strand conformation polymorphism method for detection of a novel sequence polymorphism (Ile1000Val) in human alpha(2)-macroglobulin.

Wu YY et al.

Clinical Chemistry, 2000

No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.

Wavrant-DeVrièze F et al.

Neuroscience Letters, 1999

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."