Varaico: Literature-Extracted Genetic Variants

Gene:AADAC
Variant:p.V281I
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AADAC

NM_001086.3:p.V281I

Associated Papers

Pharmacogenetics in Tuberculosis-HIV Coinfected Populations: A Systematic Review of Genetic Variants Influencing Antiretroviral and Anti-Tuberculosis Drug Response.

Hardi H et al.

Journal of Multidisciplinary Healthcare, 2025

Regulation of Human Hydrolases and Its Implications in Pharmacokinetics and Pharmacodynamics.

Jung SM et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2024

Variability in plasma rifampicin concentrations and role of SLCO1B1, ABCB1, AADAC2 and CES2 genotypes in Ethiopian patients with tuberculosis.

Sileshi T et al.

Infectious Diseases (london, England), 2024

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients.

Levano KS et al.

Molecular Genetics & Genomic Medicine, 2021

Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity.

Hirosawa K et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity.

Shimizu M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."