Associated Papers
Mapping the Role of P-gp in Multidrug Resistance: Insights from Recent Structural Studies.
Tia ST et al.
International Journal of Molecular Sciences, 2025
Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
Meijer TG et al.
Cancers, 2024
Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy.
Bagdasaryan AA et al.
Cancers, 2022
Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males.
Zahari Z et al.
Pain Practice : the Official Journal of World Institute of Pain, 2017
Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.
Apellániz-Ruiz M et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017
De novo mutations in moderate or severe intellectual disability.
Hamdan FF et al.
Plos Genetics, 2014
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.
Wang J et al.
Plos One, 2014
An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.
Wolf SJ et al.
The Pharmacogenomics Journal, 2011
P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.
Cascorbi I
Handbook of Experimental Pharmacology, 2011
Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.
Kelly L et al.
Protein Science : a Publication of the Protein Society, 2010
Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations.
Benish RL et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2010
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
Fung KL et al.
Biochimica Et Biophysica Acta, 2009
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
Substrate-dependent effects of human ABCB1 coding polymorphisms.
Gow JM et al.
The Journal of Pharmacology and Experimental Therapeutics, 2008
ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.
Leschziner GD et al.
The Pharmacogenomics Journal, 2007
Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay.
Jeong H et al.
Plos Genetics, 2007
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
Cascorbi I
Pharmacology & Therapeutics, 2006
Implications of genetic polymorphisms in drug transporters for pharmacotherapy.
Kerb R
Cancer Letters, 2006
MDR1 gene polymorphisms and clinical relevance.
Li YH et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2006
Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.
Dey S
Expert Opinion on Drug Delivery, 2006
Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.
Bosch TM et al.
Molecular Diagnosis & Therapy, 2006
[Association study between NPY and YWHAH gene polymorphisms and schizophrenia].
Wang HS et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2005
CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population.
Allabi AC et al.
Pharmacogenetics and Genomics, 2005
Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.
Sakurai A et al.
Expert Opinion on Pharmacotherapy, 2005
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005
Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population.
Allabi AC et al.
European Journal of Clinical Pharmacology, 2005
Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics.
Putnam WS et al.
Journal of Clinical Pharmacology, 2005
[Detecting genetic polymorphisms of CYP1 A1 and GSTM1 simultaneously with oligonucleotide microarray].
Liu SZ et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2004
The MDR1 (ABCB1) gene polymorphism and its clinical implications.
Ieiri I et al.
Clinical Pharmacokinetics, 2004
Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan.
Sai K et al.
Pharmacogenetics, 2003
[MDR1 genotypes related to pharmacokinetics and MDR1 expression].
Nakamura T
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan, 2003
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene.
Kroetz DL et al.
Pharmacogenetics, 2003
The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans.
Fromm MF
Advanced Drug Delivery Reviews, 2002
MDR1 genotype-related pharmacokinetics and pharmacodynamics.
Sakaeda T et al.
Biological & Pharmaceutical Bulletin, 2002
Identification of functionally variant MDR1 alleles among European Americans and African Americans.
Kim RB et al.
Clinical Pharmacology and Therapeutics, 2001
[Analysis of association between gene polymorphisms of microsomal epoxide hydrolase (EPHX1) and infant birthweight].
Wu D et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2001
[STR polymorphisms in five Chinese ethnic groups(2)].
Li SB et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2000
[DNA polymorphisms and haplotypes in the apoAI-CIII gene region and coronary heart disease].
Meng X et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 1990