Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.W1108R
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ABCB1

NM_001348946.2:p.W1108R

Associated Papers

Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy.

Bagdasaryan AA et al.

Cancers, 2022

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.

Bruhn O et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.

Wolf SJ et al.

The Pharmacogenomics Journal, 2011

Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.

Kelly L et al.

Protein Science : a Publication of the Protein Society, 2010

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Fung KL et al.

Biochimica Et Biophysica Acta, 2009

Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay.

Jeong H et al.

Plos Genetics, 2007

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.

Sakurai A et al.

Expert Opinion on Pharmacotherapy, 2005

Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene.

Kroetz DL et al.

Pharmacogenetics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."