Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.A999T
Back to variants list

ABCB1

NM_001348946.2:p.A999T

Associated Papers

Multidrug resistant 1 (MDR1) C3435T and G2677T gene polymorphism: impact on the risk of acute rejection in pediatric kidney transplant recipients.

Korkor MS et al.

Italian Journal of Pediatrics, 2023

Association of ABCB1 C3435T Polymorphism with Echocardiographic Index Among Patients with Atherosclerotic Ischemic Stroke and Transient Ischemic Attack.

Wang L et al.

Journal of Molecular Neuroscience : Mn, 2020

Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males.

Zahari Z et al.

Pain Practice : the Official Journal of World Institute of Pain, 2017

MDR1 mRNA expression and MDR1 gene variants as predictors of response to chemotherapy in patients with acute myeloid leukaemia: a meta-analysis.

Doxani C et al.

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 2013

An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.

Wolf SJ et al.

The Pharmacogenomics Journal, 2011

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.

Cascorbi I

Handbook of Experimental Pharmacology, 2011

Emerging new technologies in Pharmacogenomics: rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).

Ishikawa T et al.

Pharmacology & Therapeutics, 2010

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Fung KL et al.

Biochimica Et Biophysica Acta, 2009

A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport.

Yang Z et al.

The Journal of Pharmacology and Experimental Therapeutics, 2008

Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1).

Sakurai A et al.

Biochemistry, 2007

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

Cascorbi I

Pharmacology & Therapeutics, 2006

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.

Ieiri I et al.

Expert Opinion on Drug Metabolism & Toxicology, 2006

MDR1 gene polymorphisms and clinical relevance.

Li YH et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2006

Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.

Dey S

Expert Opinion on Drug Delivery, 2006

[Association study between NPY and YWHAH gene polymorphisms and schizophrenia].

Wang HS et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2005

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.

Sakurai A et al.

Expert Opinion on Pharmacotherapy, 2005

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.

Ishikawa T et al.

Methods in Enzymology, 2005

[Detecting genetic polymorphisms of CYP1 A1 and GSTM1 simultaneously with oligonucleotide microarray].

Liu SZ et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2004

Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein.

Woodahl EL et al.

The Journal of Pharmacology and Experimental Therapeutics, 2004

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

Ishikawa T et al.

Biological & Pharmaceutical Bulletin, 2004

Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies.

Jamroziak K et al.

Hematology (amsterdam, Netherlands), 2004

The MDR1 (ABCB1) gene polymorphism and its clinical implications.

Ieiri I et al.

Clinical Pharmacokinetics, 2004

P-glycoprotein: from genomics to mechanism.

Ambudkar SV et al.

Oncogene, 2003

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans.

Fromm MF

Advanced Drug Delivery Reviews, 2002

MDR1 genotype-related pharmacokinetics and pharmacodynamics.

Sakaeda T et al.

Biological & Pharmaceutical Bulletin, 2002

Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy.

Brinkmann U et al.

Drug Discovery Today, 2001

[Analysis of association between gene polymorphisms of microsomal epoxide hydrolase (EPHX1) and infant birthweight].

Wu D et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2001

[STR polymorphisms in five Chinese ethnic groups(2)].

Li SB et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2000

[DNA polymorphisms and haplotypes in the apoAI-CIII gene region and coronary heart disease].

Meng X et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 1990

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."