Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.M986V
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ABCB1

NM_001348946.2:p.M986V

Associated Papers

P-glycoprotein mechanical functional analysis using in silico molecular modeling: Pharmacokinetic variability according to ABCB1 c.2677G > T/A genetic polymorphisms.

Jeong SH et al.

International Journal of Biological Macromolecules, 2023

Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males.

Zahari Z et al.

Pain Practice : the Official Journal of World Institute of Pain, 2017

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.

Cascorbi I

Handbook of Experimental Pharmacology, 2011

Emerging new technologies in Pharmacogenomics: rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).

Ishikawa T et al.

Pharmacology & Therapeutics, 2010

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Fung KL et al.

Biochimica Et Biophysica Acta, 2009

Potential impact of ABCB1 (p-glycoprotein) polymorphisms on avermectin toxicity in humans.

Macdonald N et al.

Archives of Toxicology, 2007

Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1).

Sakurai A et al.

Biochemistry, 2007

Analyses of single nucleotide polymorphisms and haplotype linkage of the human ABCB1 (MDR1) gene in Korean.

Ryu HC et al.

Archives of Pharmacal Research, 2006

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

Cascorbi I

Pharmacology & Therapeutics, 2006

Genetic variations and haplotype structures of the ABCB1 gene in a Japanese population: an expanded haplotype block covering the distal promoter region, and associated ethnic differences.

Sai K et al.

Annals of Human Genetics, 2006

MDR1 gene polymorphisms and clinical relevance.

Li YH et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2006

Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.

Dey S

Expert Opinion on Drug Delivery, 2006

[Association study between NPY and YWHAH gene polymorphisms and schizophrenia].

Wang HS et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2005

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.

Sakurai A et al.

Expert Opinion on Pharmacotherapy, 2005

High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.

Ishikawa T et al.

Methods in Enzymology, 2005

[Detecting genetic polymorphisms of CYP1 A1 and GSTM1 simultaneously with oligonucleotide microarray].

Liu SZ et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2004

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

Ishikawa T et al.

Biological & Pharmaceutical Bulletin, 2004

The MDR1 (ABCB1) gene polymorphism and its clinical implications.

Ieiri I et al.

Clinical Pharmacokinetics, 2004

MDR1 genotype-related pharmacokinetics and pharmacodynamics.

Sakaeda T et al.

Biological & Pharmaceutical Bulletin, 2002

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

Kurata Y et al.

Clinical Pharmacology and Therapeutics, 2002

Polymorphism of MDR1 gene in healthy japanese subjects: a novel SNP with an amino acid substitution (Glu108Lys).

Honda T et al.

Drug Metabolism and Pharmacokinetics, 2002

[Analysis of association between gene polymorphisms of microsomal epoxide hydrolase (EPHX1) and infant birthweight].

Wu D et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2001

[STR polymorphisms in five Chinese ethnic groups(2)].

Li SB et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2000

[DNA polymorphisms and haplotypes in the apoAI-CIII gene region and coronary heart disease].

Meng X et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 1990

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."