Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.V981A
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ABCB1

NM_001348946.2:p.V981A

Associated Papers

In vitro identification of decreased function genetic variants of ABCB1.

Suominen L et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2025

Conversion of Human Multidrug Transporter P-glycoprotein (ABCB1) from Drug Efflux to Uptake Pump: Evidence for a Switch Region Modulating the Direction of Substrate Transport.

Sajid A et al.

Journal of Molecular Biology, 2025

Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein.

Sajid A et al.

Proceedings of the National Academy of Sciences of the United States of America, 2020

Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein.

Hafkemeyer P et al.

Biochemistry, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."