Associated Papers
In vitro identification of decreased function genetic variants of ABCB1.
Suominen L et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2025
In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals.
Schäfer J et al.
International Journal of Molecular Sciences, 2023
Theoretical insights on helix repacking as the origin of P-glycoprotein promiscuity.
Bonito CA et al.
Scientific Reports, 2020
Drug-protein hydrogen bonds govern the inhibition of the ATP hydrolysis of the multidrug transporter P-glycoprotein.
Chufan EE et al.
Biochemical Pharmacology, 2016
Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1).
Chufan EE et al.
Plos One, 2013
Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar residues important for drug transport.
Ni Z et al.
American Journal of Physiology. Cell Physiology, 2010
Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1.
Crowley E et al.
Biochemistry, 2009
Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM12 of human P-glycoprotein by drug substrates.
Loo TW et al.
The Journal of Biological Chemistry, 1996
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