Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.S893A
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ABCB1

NM_001348946.2:p.S893A

Associated Papers

Clinical Implementation of Pharmacogenomics and Drug-Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow-Up.

Tremmel R et al.

Clinical Pharmacology and Therapeutics, 2026

41074844 (PubMed )
Supplement: CPT-119-241-s005.pdf

Molecular analysis of the evolutionary history of endometrial and ovarian carcinoma in Lynch syndrome.

Kauppinen AK et al.

International Journal of Cancer, 2025

40772756 (PubMed )
Supplement: IJC-157-2294-s002.xlsx › B_Tissue_as_normal

Influence of genetic polymorphisms on gefitinib pharmacokinetics and adverse drug reactions in non-small cell lung cancer patients.

Shenoy PV et al.

Cancer Metastasis Reviews, 2025

An Investigational Study on the Role of ADME Agents' Genetic Variation on DD217 Pharmacokinetics and Safety Profile.

Sychev DA et al.

Pharmaceuticals (basel, Switzerland), 2025

Impact of Xenobiotic Detoxification Gene Polymorphisms on Steady-State Plasma Concentrations of Apixaban and the Development of Hemorrhagic Complications in Older Patients with Non-Valvular Atrial Fibrillation.

Kondrakhin AP et al.

Genes, 2025

Pharmacogenomics in cardiac therapy: Personalizing treatment for heart health.

Naderi N et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2025

Genetic Modulation of Silodosin Exposure and Efficacy: The Role of CYP3A4, CYP3A5, and UGT2B7 Polymorphisms in Benign Prostatic Hyperplasia Management.

Abdullaev SP et al.

Journal of Personalized Medicine, 2025

Association of ABCB1 G2677T polymorphism with atorvastatin lipid efficacy and extended prognosis in patients with cerebral ischemic stroke.

Tian Y et al.

Scientific Reports, 2025

In vitro identification of decreased function genetic variants of ABCB1.

Suominen L et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2025

In vitro assessment of ATP-binding cassette transporters and their functional genetic polymorphisms on fluoroquinolone accumulation in human embryonic kidney 293 recombinant cell lines.

Mahieu G et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

Mapping the Role of P-gp in Multidrug Resistance: Insights from Recent Structural Studies.

Tia ST et al.

International Journal of Molecular Sciences, 2025

Association of ABC Efflux Transporter Genetic Variants and Adverse Drug Reactions and Survival in Patients with Non-Small Lung Cancer.

Seguin CS et al.

Genes, 2025

40282412 (PubMed )
Supplement: genes-16-00453-s001.zip › genes-3554063-supplementary.pdf

ABCB1 gene single nucleotide variants and haplotypes in atrial fibrillation patients experiencing adverse events on direct oral anticoagulation: a whole gene exome sequencing study.

Samoš M et al.

Journal of Cardiovascular Pharmacology, 2025

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

Novel nonsense mutation in gene CHRNA2 identified by whole-genome sequencing in infant with epilepsy disorder: A case report.

Makhmetov S et al.

Heliyon, 2025

39834405 (PubMed )
Supplement: mmc4.xlsx › Sheet1

Pharmacogenetics of Neoadjuvant MAP Chemotherapy in Localized Osteosarcoma: A Study Based on Data from the GEIS-33 Protocol.

Salazar J et al.

Pharmaceutics, 2024

Computational Analysis of MDR1 Variants Predicts Effect on Cancer Cells via their Effect on mRNA Folding.

Gutman T et al.

Plos Computational Biology, 2024

CYP3A4*1B but Not CYP3A5*3 as Determinant of Long-Term Tacrolimus Dose Requirements in Spanish Solid Organ Transplant Patients.

Concha J et al.

International Journal of Molecular Sciences, 2024

Successful rapid improvement of acute respiratory distress syndrome induced by EGFR-mutated non-small cell lung cancer with almonertinib: a case report.

Sun C et al.

Bmc Pulmonary Medicine, 2024

39334060 (PubMed )
Supplement: 12890_2024_3292_MOESM1_ESM.xlsx › Mutations

Challenging pharmacotherapy management of a psychotic disorder due to a delicate pharmacogenetic profile and drug-drug interactions: a case report and literature review.

Belančić A et al.

Croatian Medical Journal, 2024

ERCC1 and ERCC2 Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer.

Barba A et al.

Pharmaceutics, 2024

Characterization of Chemoresistance in Pancreatic Cancer: A Look at MDR-1 Polymorphisms and Expression in Cancer Cells and Patients.

Girolimetti G et al.

International Journal of Molecular Sciences, 2024

Genetic Variation in ABCB1, ADRB1, CYP3A4, CYP3A5, NEDD4L and NR3C2 Confers Differential Susceptibility to Resistant Hypertension among South Africans.

Katsukunya JN et al.

Journal of Personalized Medicine, 2024

Case Report: Life-Threatening Fluoxetine-Linked Postoperative Bleeding Informed by Pharmacogenetic Evaluation.

Rogers S et al.

Drugs in R&d, 2024

Toward Genetic Testing of Rivaroxaban? Insights from a Systematic Review on the Role of Genetic Polymorphism in Rivaroxaban Therapy.

Ma Y et al.

Clinical Pharmacokinetics, 2024

Case report: Avoiding intolerance to antipsychotics through a personalized treatment approach based on pharmacogenetics.

Korošec Hudnik L et al.

Frontiers in Psychiatry, 2024

The use of therapeutic drug monitoring to highlight an over-looked drug-drug interaction leading to imatinib treatment failure.

Gagno S et al.

Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2023

Population pharmacokinetics of oxcarbazepine active metabolite in Chinese children with epilepsy.

Li X et al.

European Journal of Pediatrics, 2023

Pharmacogenetic Variants Associated with Fluoxetine Pharmacokinetics from a Bioequivalence Study in Healthy Subjects.

Díaz-Tufinio CA et al.

Journal of Personalized Medicine, 2023

Bearing variant alleles at uridine glucuronosyltransferase polymorphisms UGT2B7 -161C > T (rs7668258) or UGT1A4*3 c.142 T > G (rs2011425) has no relevant consequences for lamotrigine troughs in adults with epilepsy.

Božina N et al.

European Journal of Clinical Pharmacology, 2023

Importance of Pharmacogenetics and Drug-Drug Interactions in a Kidney Transplanted Patient.

Concha J et al.

Life (basel, Switzerland), 2023

Pharmacogenomic variation in the Malagasy population: implications for the antimalarial drug primaquine metabolism.

Cramer EY et al.

Pharmacogenomics, 2023

Molecular and Clinical Links between Drug-Induced Cholestasis and Familial Intrahepatic Cholestasis.

Vitale G et al.

International Journal of Molecular Sciences, 2023

Pilot Study on the Impact of Polymorphisms Linked to Multi-Kinase Inhibitor Metabolism on Lenvatinib Side Effects in Patients with Advanced Thyroid Cancer.

Cantara S et al.

International Journal of Molecular Sciences, 2023

Effect of Genotype on the Pharmacokinetics and Bleeding Events of Direct Oral Anticoagulants: A Systematic Review and Meta-analysis.

Shi J et al.

Journal of Clinical Pharmacology, 2023

Importance of selected ABCB1 SNPs for the level of severity of depressive symptoms and effectiveness of recurrent depressive disorder therapy.

Jeleń A et al.

Gene, 2023

Analytical validation of GenoPharm a clinical genotyping open array panel of 46 pharmacogenes inclusive of variants unique to people of African ancestry.

Kanji CR et al.

Plos One, 2023

Polymorphisms in drug metabolism genes predict the risk of refractory myasthenia gravis.

Zhang Q et al.

Annals of Translational Medicine, 2022

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis.

Alves R et al.

International Journal of Molecular Sciences, 2022

36077209 (PubMed )
Supplement: ijms-23-09815-s001.zip › ijms-1852648-supplementary.pdf

Composite CYP3A phenotypes influence tacrolimus dose-adjusted concentration in lung transplant recipients.

Liu M et al.

Pharmacogenetics and Genomics, 2022

Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers.

Bignucolo A et al.

Expert Review of Clinical Pharmacology, 2022

Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.

Dagli-Hernandez C et al.

Pharmaceutics, 2022

Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts.

Dagli-Hernandez C et al.

Pharmacological Reports : Pr, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."