Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.S893T
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ABCB1

NM_001348946.2:p.S893T

Associated Papers

Clinical Implementation of Pharmacogenomics and Drug-Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow-Up.

Tremmel R et al.

Clinical Pharmacology and Therapeutics, 2026

41074844 (PubMed )
Supplement: CPT-119-241-s005.pdf

Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.

Twesigomwe D et al.

Scientific Reports, 2025

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants.

Thorsen SV et al.

Basic & Clinical Pharmacology & Toxicology, 2025

Pharmacogenetic Implications for Antidepressant Therapy in Major Depression: A Systematic Review Covering 2019-2024.

Fornaguera A et al.

Journal of Clinical Medicine, 2025

40725795 (PubMed )
Supplement: jcm-14-05102-s001.zip › jcm-3736459-supplementary.pdf

In vitro identification of decreased function genetic variants of ABCB1.

Suominen L et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2025

Computational studies on the functional and structural impact of pathogenic mutations in enzymes.

Dissanayake UC et al.

Protein Science : a Publication of the Protein Society, 2025

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

Pharmacogenetics of Neoadjuvant MAP Chemotherapy in Localized Osteosarcoma: A Study Based on Data from the GEIS-33 Protocol.

Salazar J et al.

Pharmaceutics, 2024

ERCC1 and ERCC2 Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer.

Barba A et al.

Pharmaceutics, 2024

Genome-Wide Association Study of Atorvastatin Pharmacokinetics: Associations With SLCO1B1, UGT1A3, and LPP.

Mykkänen AJH et al.

Clinical Pharmacology and Therapeutics, 2024

Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma.

Patiño-García A et al.

Ebiomedicine, 2024

38484556 (PubMed )
Supplement: mmc1.xlsx › Supp_Table_2

Case Report: Life-Threatening Fluoxetine-Linked Postoperative Bleeding Informed by Pharmacogenetic Evaluation.

Rogers S et al.

Drugs in R&d, 2024

Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.

Meijer TG et al.

Cancers, 2024

38398132 (PubMed )
Supplement: cancers-16-00741-s001.zip › Table_S1-2_WES_results.xlsx › Table_S2

Association of Gene Polymorphisms with Breast Cancer Risk in the Kazakh Population.

Shanazarov N et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

Dosage optimization of tacrolimus based on the glucocorticoid dose and pharmacogenetics in adult patients with systemic lupus erythematosus.

Wang CB et al.

International Immunopharmacology, 2023

Association of ADME gene polymorphisms on toxicity to CDK4/6 inhibitors in patients with HR+ HER2- metastatic breast cancer.

Peruzzi E et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2023

Genetic variations in ABC transporter genes as a predictive biomarker for toxicity in North Indian lung cancer patients undergoing platinum-based doublet chemotherapy.

Sharma P et al.

Journal of Biochemical and Molecular Toxicology, 2023

Importance of selected ABCB1 SNPs for the level of severity of depressive symptoms and effectiveness of recurrent depressive disorder therapy.

Jeleń A et al.

Gene, 2023

Impact of ABCB1, ABCC1, ABCC2, and ABCG2 variants in predicting prognosis and clinical outcomes of north Indian lung cancer patients undergoing platinum-based doublet chemotherapy.

Sharma P et al.

The Journal of Gene Medicine, 2023

Pharmacogenetics of anxiety and depression in Alzheimer's disease.

Cacabelos R et al.

Pharmacogenomics, 2023

The Interaction between Four Polymorphisms and Haplotype of ABCB1, the Risk of Non-Small Cell Lung Cancer, and the Disease Phenotype.

Jeleń A et al.

Journal of Oncology, 2023

Common ABCB1 SNP, C3435T could affect systemic exposure of dapagliflozin in healthy subject.

Hwang JG et al.

Translational and Clinical Pharmacology, 2022

Polymorphisms in drug metabolism genes predict the risk of refractory myasthenia gravis.

Zhang Q et al.

Annals of Translational Medicine, 2022

Pharmacogenomics of celiprolol - evidence for a role of P-glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics.

Hirvensalo P et al.

Clinical and Translational Science, 2022

Detection of Tri-allelic Single Nucleotide Polymorphisms of ABCB1 and CRP Genes by Penta-Primer Amplification Refractory Mutation System-Polymerase Chain Reaction.

Yang S et al.

Genetic Testing and Molecular Biomarkers, 2022

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table1.xlsx › Hoja1

Whole-exome sequencing expands the roles of novel mutations of organic anion transporting polypeptide, ATP-binding cassette transporter, and receptor genes in intrahepatic cholestasis of pregnancy.

Liu X et al.

Frontiers in Genetics, 2022

36046230 (PubMed )
Supplement: Table3.XLSX › Sheet1

Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients.

Campos-Staffico AM et al.

Frontiers in Pharmacology, 2022

Computational validation of ABCB1 gene polymorphism and its effect on tacrolimus dose concentration/levels in renal transplant individuals of South India.

Mallina H et al.

Computers in Biology and Medicine, 2021

Polymorphism in drug transporter gene ABCB1 is associated with drug resistance in Pakistani epilepsy patients.

Maqbool H et al.

Epilepsy Research, 2021

Assessment of the Link of ABCB1 and NR3C1 gene polymorphisms with the prednisolone resistance in pediatric nephrotic syndrome patients of Bangladesh: A genotype and haplotype approach.

Parvin MN et al.

Journal of Advanced Research, 2021

Estrogen profile- and pharmacogenetics-based lamotrigine dosing regimen optimization: Recommendations for pregnant women with epilepsy.

Wang ML et al.

Pharmacological Research, 2021

Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs.

Badary OA

The Pharmacogenomics Journal, 2021

Comprehensive pharmacogenetic analysis of DPYD, UGT, CDA, and ABCB1 polymorphisms in pancreatic cancer patients receiving mFOLFIRINOX or gemcitabine plus nab-paclitaxel.

Vivaldi C et al.

The Pharmacogenomics Journal, 2021

Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Scott SA et al.

Clinical and Translational Science, 2021

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

NGS study of glucocorticoid response genes in inflammatory bowel disease patients.

Skrzypczak-Zielinska M et al.

Archives of Medical Science : Ams, 2021

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Effects of CYP3A5, ABCB1 and POR*28 polymorphisms on pharmacokinetics of tacrolimus in the early period after renal transplantation.

Ling J et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Li J et al.

Journal of Translational Medicine, 2020

32738923 (PubMed )
Supplement: 12967_2020_2449_MOESM2_ESM.xlsx › Supplementary_Table_S1

Melding Pharmacogenomic Effect of MDR1 and CYP3A5 Gene Polymorphism on Tacrolimus Dosing in Renal Transplant Recipients in Northern India.

Prasad N et al.

Kidney International Reports, 2020

Pharmacogenetics of Atremorine-Induced Neuroprotection and Dopamine Response in Parkinson's Disease.

Cacabelos R et al.

Planta Medica, 2019

ABCB1 polymorphism predicts the toxicity and clinical outcome of lung cancer patients with taxane-based chemotherapy.

Zhong J et al.

Thoracic Cancer, 2019

The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome.

Coller JK et al.

British Journal of Clinical Pharmacology, 2019

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis.

Yang J et al.

Bioscience Reports, 2019

Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity.

Crocco P et al.

Genes, 2019

31137904 (PubMed )
Supplement: genes-10-00403-s001.pdf

Pharmacogenetics of Membrane Transporters of Tacrolimus in Solid Organ Transplantation.

Tron C et al.

Clinical Pharmacokinetics, 2019

Tumor mutation burden and recurrent tumors in hereditary lung cancer.

Hsu YC et al.

Cancer Medicine, 2019

30941903 (PubMed )
Supplement: CAM4-8-2179-s001.xlsx › S2
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."