Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.G830V
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ABCB1

NM_001348946.2:p.G830V

Associated Papers

Long-range communication between transmembrane- and nucleotide-binding domains does not depend on drug binding to mutant P-glycoprotein.

Bonito CA et al.

Journal of Biomolecular Structure & Dynamics, 2023

Theoretical insights on helix repacking as the origin of P-glycoprotein promiscuity.

Bonito CA et al.

Scientific Reports, 2020

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Fung KL et al.

Biochimica Et Biophysica Acta, 2009

Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

Loo TW et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."