Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.K433T
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ABCB1

NM_001348946.2:p.K433T

Associated Papers

Role of common host genome variants in Childhood Acute Lymphoblastic Leukemia.

Mikkelsen T et al.

Leukemia, 2026

41361660 (PubMed )
Supplement: 41375_2025_2804_MOESM1_ESM.docx

Genetics are not likely to offer clinically useful predictions for elevated liver enzyme levels in patients using low dose methotrexate.

Cui J et al.

Seminars in Arthritis and Rheumatism, 2022

Genetic Predictors for Sinusoidal Obstruction Syndrome-A Systematic Review.

Waespe N et al.

Journal of Personalized Medicine, 2021

Effect of Polymorphisms of ABCB1 and MTHFR on Methotrexate-Related Toxicities in Adults With Hematological Malignancies.

Han J et al.

Frontiers in Oncology, 2021

35004279 (PubMed )
Supplement: Table_2.xlsx › Sheet1

Genetic Polymorphisms Associated with Rheumatoid Arthritis Development and Antirheumatic Therapy Response.

Mikhaylenko DS et al.

International Journal of Molecular Sciences, 2020

Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer.

López-Cortés A et al.

The Pharmacogenomics Journal, 2020

The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance Treatment.

Rudin S et al.

Genomics, Proteomics & Bioinformatics, 2017

The effect of gene polymorphisms on patient responses to rheumatoid arthritis therapy.

Tarnowski M et al.

Expert Opinion on Drug Metabolism & Toxicology, 2016

Germline oncopharmacogenetics, a promising field in cancer therapy.

Pesenti C et al.

Cellular Oncology (dordrecht, Netherlands), 2015

Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.

Dulucq S et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia.

Lu Y et al.

British Journal of Cancer, 2014

24434428 (PubMed )
Supplement: bjc20147x1.doc

Lack of association between polymorphisms in genes MTHFR and MDR1 with risk of childhood acute lymphoblastic leukemia.

Kreile M et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review).

Martino A et al.

International Journal of Oncology, 2012

Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.

Cecchin E et al.

The Pharmacogenomics Journal, 2011

Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia.

Rocha V et al.

Leukemia, 2009

Pharmacogenetics in chemotherapy of colorectal cancer.

Henriette Tanja L et al.

Best Practice & Research. Clinical Gastroenterology, 2009

Pharmacogenetics of acute lymphoblastic leukemia treatment response.

Cunningham L et al.

Expert Opinion on Pharmacotherapy, 2007

Pharmacogenetics for individualized cancer chemotherapy.

Efferth T et al.

Pharmacology & Therapeutics, 2005

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy.

Toffoli G et al.

Journal of Chemotherapy (florence, Italy), 2004

Pharmacogenetics of disease-modifying anti-rheumatic drugs.

Tanaka E et al.

Best Practice & Research. Clinical Rheumatology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."