Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.S400I
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ABCB1

NM_001348946.2:p.S400I

Associated Papers

Association of ABCB1 and VEGFA gene polymorphisms with breast cancer susceptibility and prognosis.

Madrid-Paredes A et al.

Pathology, Research and Practice, 2020

Polymorphisms in the ABCB1 gene and effect on outcome and toxicity in childhood acute lymphoblastic leukemia.

Gregers J et al.

The Pharmacogenomics Journal, 2015

Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel.

Njiaju UO et al.

Pharmacogenetics and Genomics, 2012

Pharmacogenetics of genes across the doxorubicin pathway.

Jamieson D et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Cytochrome P450 and ABCB1 genetics: association with quetiapine and norquetiapine plasma and cerebrospinal fluid concentrations and with clinical response in patients suffering from schizophrenia. A pilot study.

Nikisch G et al.

Journal of Psychopharmacology (oxford, England), 2011

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.

Cascorbi I

Handbook of Experimental Pharmacology, 2011

Polymorphisms in ABCB1 and ERCC2 associated with ovarian cancer outcome.

Peethambaram P et al.

International Journal of Molecular Epidemiology and Genetics, 2011

A novel MDR1 GT1292-3TG (Cys431Leu) genetic variation and its effect on P-glycoprotein biologic functions.

Crouthamel MH et al.

The Aaps Journal, 2010

A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport.

Yang Z et al.

The Journal of Pharmacology and Experimental Therapeutics, 2008

ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel.

Gréen H et al.

Journal of Pharmaceutical Sciences, 2008

Influence of ABCB1 genetic polymorphisms on cyclosporine intracellular concentration in transplant recipients.

Crettol S et al.

Pharmacogenetics and Genomics, 2008

A novel MDR1 G1199T variant alters drug resistance and efflux transport activity of P-glycoprotein in recombinant Hek cells.

Crouthamel MH et al.

Journal of Pharmaceutical Sciences, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."