Associated Papers
The potential of deep learning on the discovery of new genes implicated in differences of sex development.
von der Decken I et al.
Computational and Structural Biotechnology Journal, 2026
Association between ABCB1 C3435 T polymorphism- and methotrexate-related toxicity in pediatric acute lymphoblastic leukemia: a meta-analysis.
Yan X et al.
Hematology (amsterdam, Netherlands), 2025
A Population Pharmacokinetic Model and Dosing Algorithm to Guide the Tacrolimus Starting and Follow-Up Dose in Living and Deceased Donor Kidney Transplant Recipients.
Francke MI et al.
Clinical Pharmacokinetics, 2025
Dolutegravir and Risk of Neuropsychiatric Adverse Events: A Pharmacogenetic Study.
De Greef J et al.
The Journal of Infectious Diseases, 2025
Pharmacogenetic Biomarkers of Ibrutinib Response and Toxicity in Chronic Lymphocytic Leukemia: Insights from an Observational Study.
Pérez-Gómez N et al.
Pharmaceuticals (basel, Switzerland), 2025
In vitro assessment of ATP-binding cassette transporters and their functional genetic polymorphisms on fluoroquinolone accumulation in human embryonic kidney 293 recombinant cell lines.
Mahieu G et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025
Mapping the Role of P-gp in Multidrug Resistance: Insights from Recent Structural Studies.
Tia ST et al.
International Journal of Molecular Sciences, 2025
ABCB1 gene single nucleotide variants and haplotypes in atrial fibrillation patients experiencing adverse events on direct oral anticoagulation: a whole gene exome sequencing study.
Samoš M et al.
Journal of Cardiovascular Pharmacology, 2025
Impact of CYP3A4 and ABCB1 genetic variants on tacrolimus dosing in Greek kidney transplant recipients.
Tsironi A et al.
Frontiers in Pharmacology, 2025
Effect of ABCB1 most frequent polymorphisms on the accumulation of bictegravir in recombinant HEK293 cell lines.
De Greef J et al.
Scientific Reports, 2024
A systematic review and meta-analysis of the impacts of germline pharmacogenomics on severe toxicity and symptom burden in adult patients with cancer.
Lingaratnam S et al.
Clinical and Translational Science, 2024
Effects of gene polymorphisms on delayed MTX clearance, toxicity, and metabolomic changes after HD-MTX treatment in children with acute lymphoblastic leukemia.
Zhou Y et al.
European Journal of Pediatrics, 2024
Association between genetic variants of transmembrane transporters and susceptibility to anthracycline-induced cardiotoxicity: Current understanding and existing evidence.
Ni MM et al.
Clinical Genetics, 2024
Population pharmacokinetics of lenalidomide in Chinese patients with influence of genetic polymorphisms of ABCB1.
Liang X et al.
Scientific Reports, 2024
Pharmacogenetics of anxiety and depression in Alzheimer's disease.
Cacabelos R et al.
Pharmacogenomics, 2023
Drug transporters are implicated in the diffusion of tacrolimus into the T lymphocyte in kidney and liver transplant recipients: Genetic, mRNA, protein expression, and functionality.
Coste G et al.
Drug Metabolism and Pharmacokinetics, 2022
Pharmacogenetic Study of the Impact of ABCB1 Single Nucleotide Polymorphisms on the Response to Cyclosporine in Psoriasis Patients.
Chernov A et al.
Pharmaceutics, 2022
Insights into the Pharmacogenetics of Tacrolimus Pharmacokinetics and Pharmacodynamics.
Brunet M et al.
Pharmaceutics, 2022
Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants.
Sridharan K et al.
Journal of Personalized Medicine, 2022
Atorvastatin population pharmacokinetics in a real-life setting: Influence of genetic polymorphisms and association with clinical response.
Stillemans G et al.
Clinical and Translational Science, 2022
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Silgado-Guzmán DF et al.
Frontiers in Pharmacology, 2022
Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs.
Badary OA
The Pharmacogenomics Journal, 2021
Effect of four ABCB1 genetic polymorphisms on the accumulation of darunavir in HEK293 recombinant cell lines.
Stillemans G et al.
Scientific Reports, 2021
Pharmacogenomics biomarkers for personalized methadone maintenance treatment: The mechanism and its potential use.
Ramli FF
Bosnian Journal of Basic Medical Sciences, 2021
ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?
Bruckmueller H et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
Update on drug transporter proteins in acute myeloid leukemia: Pathological implication and clinical setting.
Vasconcelos FC et al.
Critical Reviews in Oncology/hematology, 2021
Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters.
Iannaccone T et al.
Pharmaceuticals (basel, Switzerland), 2021
Pharmacogenomics of anticancer drugs: Personalising the choice and dose to manage drug response.
Carr DF et al.
British Journal of Clinical Pharmacology, 2021
Contribution of rare genetic variants to drug response in absence epilepsy.
Myers KA et al.
Epilepsy Research, 2021
Early impact of donor CYP3A5 genotype and Graft-to-Recipient Weight Ratio on tacrolimus pharmacokinetics in pediatric liver transplant patients.
Pinon M et al.
Scientific Reports, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
NGS study of glucocorticoid response genes in inflammatory bowel disease patients.
Skrzypczak-Zielinska M et al.
Archives of Medical Science : Ams, 2021
Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk Factor.
Yang QY et al.
Frontiers in Pharmacology, 2021
Failure of Achieving Tacrolimus Target Blood Concentration Might Be Avoided by a Wide Genotyping of Transplanted Patients: Evidence from a Retrospective Study.
Pallio G et al.
Journal of Personalized Medicine, 2020
Ethnogeographic and inter-individual variability of human ABC transporters.
Xiao Q et al.
Human Genetics, 2020
ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide.
Malmström A et al.
The Pharmacogenomics Journal, 2020
The role of candidate genetic polymorphisms in the interaction between voriconazole and cyclosporine in patients undergoing allogeneic hematopoietic cell transplantation: An explorative study.
Zgheib NK et al.
Current Research in Translational Medicine, 2020
Influence of ABCB1 (1236C > T, 2677G > T and 3435C > T) polymorphisms on the transport ability of P-gp-mediated sunitinib in Caco-2 cell line.
Tan DQ
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020
The influence of single-nucleotide polymorphisms on overall survival and toxicity in cabazitaxel-treated patients with metastatic castration-resistant prostate cancer.
Belderbos BPS et al.
Cancer Chemotherapy and Pharmacology, 2020
Pharmacogenetic-Whole blood and intracellular pharmacokinetic-Pharmacodynamic (PG-PK2-PD) relationship of tacrolimus in liver transplant recipients.
Tron C et al.
Plos One, 2020
Association of a genetic variant in ATP-binding cassette sub-family B member 1 gene with poor prognosis in patients with squamous cell carcinoma of the esophagus.
Rastgar-Moghadam A et al.
Iubmb Life, 2019
The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome.
Coller JK et al.
British Journal of Clinical Pharmacology, 2019
Correlation Between C3435T Locus of ABCB1 Gene and Poststroke Depression in China.
Ding X et al.
Dna and Cell Biology, 2019
ABCB1 2677G>T single nucleotide polymorphism influences warfarin dose requirement for warfarin maintenance therapy.
Mg G et al.
British Journal of Biomedical Science, 2019
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
Influence of ABCB1 polymorphisms on the pharmacokinetics and toxicity of lenalidomide in patients with multiple myeloma.
Kobayashi T et al.
Medical Oncology (northwood, London, England), 2019