Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.W232*
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ABCB1

NM_001348946.2:p.W232*

Associated Papers

Impact of polymorphisms in transporter and metabolizing enzyme genes on olanzapine pharmacokinetics and safety in healthy volunteers.

Zubiaur P et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2021

The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants.

Loo TW et al.

Biochemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."