Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.W232R
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ABCB1

NM_001348946.2:p.W232R

Associated Papers

Corrector VX-809 stabilizes the first transmembrane domain of CFTR.

Loo TW et al.

Biochemical Pharmacology, 2013

A salt bridge in intracellular loop 2 is essential for folding of human p-glycoprotein.

Loo TW et al.

Biochemistry, 2013

The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants.

Loo TW et al.

Biochemistry, 2011

Identification of residues in the drug translocation pathway of the human multidrug resistance P-glycoprotein by arginine mutagenesis.

Loo TW et al.

The Journal of Biological Chemistry, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."