Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.T215S
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ABCB1

NM_001348946.2:p.T215S

Associated Papers

Relative contributions of the ERG11VF125AL and MRR1AN647T mutations to fluconazole resistance in Clade III Candidozyma (Candida) auris clinical isolates.

Barker KS et al.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 2026

Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans.

Flowers SA et al.

Eukaryotic Cell, 2012

An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans.

Heilmann CJ et al.

Antimicrobial Agents and Chemotherapy, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."