Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.F208S
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ABCB1

NM_001348946.2:p.F208S

Associated Papers

Medically Important Alterations in Transport Function and Trafficking of ABCG2.

Homolya L

International Journal of Molecular Sciences, 2021

Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics.

Heyes N et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018

Polymorphisms of ABCG2 and its impact on clinical relevance.

Zhang W et al.

Biochemical and Biophysical Research Communications, 2018

Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.

Noguchi K et al.

Pharmacogenomics and Personalized Medicine, 2014

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.

Nakanishi T et al.

Chinese Journal of Cancer, 2012

BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization.

Shigeta J et al.

Cancer Science, 2010

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.

Noguchi K et al.

Advanced Drug Delivery Reviews, 2009

The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein.

Yoshioka S et al.

Pharmaceutical Research, 2007

Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development.

Yanase K et al.

Cancer Letters, 2006

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.

Sakurai A et al.

Expert Opinion on Pharmacotherapy, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."