Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.F193S
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ABCB1

NM_001348946.2:p.F193S

Associated Papers

A conserved interdomain communication pathway of pseudosymmetrically distributed residues affects substrate specificity of the fungal multidrug transporter Cdr1p.

Kolaczkowski M et al.

Biochimica Et Biophysica Acta, 2013

Insight in eukaryotic ABC transporter function by mutation analysis.

Frelet A et al.

Febs Letters, 2006

Subunit interactions in ABC transporters: towards a functional architecture.

Jones PM et al.

Fems Microbiology Letters, 1999

Mutations in the nucleotide-binding sites of P-glycoprotein that affect substrate specificity modulate substrate-induced adenosine triphosphatase activity.

Beaudet L et al.

Biochemistry, 1998

Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles.

Beaudet L et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."