Associated Papers
G521 is the gatekeeper and a key transmembrane domain contact residue of Candida albicans Cdr1.
Zhao M et al.
Mbio, 2026
In vitro identification of decreased function genetic variants of ABCB1.
Suominen L et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2025
Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
Meijer TG et al.
Cancers, 2024
Contribution of rare genetic variants to drug response in absence epilepsy.
Myers KA et al.
Epilepsy Research, 2021
Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males.
Zahari Z et al.
Pain Practice : the Official Journal of World Institute of Pain, 2017
Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.
Apellániz-Ruiz M et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017
De novo mutations in moderate or severe intellectual disability.
Hamdan FF et al.
Plos Genetics, 2014
An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.
Wolf SJ et al.
The Pharmacogenomics Journal, 2011
P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.
Cascorbi I
Handbook of Experimental Pharmacology, 2011
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
Cascorbi I
Pharmacology & Therapeutics, 2006
MDR1 gene polymorphisms and clinical relevance.
Li YH et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2006
Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.
Dey S
Expert Opinion on Drug Delivery, 2006
[Association study between NPY and YWHAH gene polymorphisms and schizophrenia].
Wang HS et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2005
Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.
Sakurai A et al.
Expert Opinion on Pharmacotherapy, 2005
High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.
Ishikawa T et al.
Methods in Enzymology, 2005
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis.
Potocnik U et al.
Genes and Immunity, 2004
[Detecting genetic polymorphisms of CYP1 A1 and GSTM1 simultaneously with oligonucleotide microarray].
Liu SZ et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2004
The MDR1 (ABCB1) gene polymorphism and its clinical implications.
Ieiri I et al.
Clinical Pharmacokinetics, 2004
Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan.
Sai K et al.
Pharmacogenetics, 2003
[MDR1 genotypes related to pharmacokinetics and MDR1 expression].
Nakamura T
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan, 2003
The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans.
Fromm MF
Advanced Drug Delivery Reviews, 2002
MDR1 genotype-related pharmacokinetics and pharmacodynamics.
Sakaeda T et al.
Biological & Pharmaceutical Bulletin, 2002
Identification of functionally variant MDR1 alleles among European Americans and African Americans.
Kim RB et al.
Clinical Pharmacology and Therapeutics, 2001
[Analysis of association between gene polymorphisms of microsomal epoxide hydrolase (EPHX1) and infant birthweight].
Wu D et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2001
[STR polymorphisms in five Chinese ethnic groups(2)].
Li SB et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 2000
[DNA polymorphisms and haplotypes in the apoAI-CIII gene region and coronary heart disease].
Meng X et al.
Yi Chuan Xue Bao = Acta Genetica Sinica, 1990