Varaico: Literature-Extracted Genetic Variants

Gene:ABCB1
Variant:p.F103L
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ABCB1

NM_001348946.2:p.F103L

Associated Papers

Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males.

Zahari Z et al.

Pain Practice : the Official Journal of World Institute of Pain, 2017

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Fung KL et al.

Biochimica Et Biophysica Acta, 2009

A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport.

Yang Z et al.

The Journal of Pharmacology and Experimental Therapeutics, 2008

Substrate-dependent effects of human ABCB1 coding polymorphisms.

Gow JM et al.

The Journal of Pharmacology and Experimental Therapeutics, 2008

ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.

Leschziner GD et al.

The Pharmacogenomics Journal, 2007

Analyses of single nucleotide polymorphisms and haplotype linkage of the human ABCB1 (MDR1) gene in Korean.

Ryu HC et al.

Archives of Pharmacal Research, 2006

MDR1 gene polymorphisms and clinical relevance.

Li YH et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2006

Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.

Dey S

Expert Opinion on Drug Delivery, 2006

[Association study between NPY and YWHAH gene polymorphisms and schizophrenia].

Wang HS et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2005

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics.

Putnam WS et al.

Journal of Clinical Pharmacology, 2005

[Detecting genetic polymorphisms of CYP1 A1 and GSTM1 simultaneously with oligonucleotide microarray].

Liu SZ et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2004

Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein.

Woodahl EL et al.

The Journal of Pharmacology and Experimental Therapeutics, 2004

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

Ishikawa T et al.

Biological & Pharmaceutical Bulletin, 2004

The MDR1 (ABCB1) gene polymorphism and its clinical implications.

Ieiri I et al.

Clinical Pharmacokinetics, 2004

P-glycoprotein: from genomics to mechanism.

Ambudkar SV et al.

Oncogene, 2003

Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene.

Kroetz DL et al.

Pharmacogenetics, 2003

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans.

Fromm MF

Advanced Drug Delivery Reviews, 2002

The transmembrane domains of the ABC multidrug transporter LmrA form a cytoplasmic exposed, aqueous chamber within the membrane.

Poelarends GJ et al.

The Journal of Biological Chemistry, 2002

MDR1 genotype-related pharmacokinetics and pharmacodynamics.

Sakaeda T et al.

Biological & Pharmaceutical Bulletin, 2002

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation.

Goto M et al.

Pharmacogenetics, 2002

Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.

Kimchi-Sarfaty C et al.

Molecular Pharmacology, 2002

Polymorphism of MDR1 gene in healthy japanese subjects: a novel SNP with an amino acid substitution (Glu108Lys).

Honda T et al.

Drug Metabolism and Pharmacokinetics, 2002

Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy.

Brinkmann U et al.

Drug Discovery Today, 2001

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

Cascorbi I et al.

Clinical Pharmacology and Therapeutics, 2001

[Analysis of association between gene polymorphisms of microsomal epoxide hydrolase (EPHX1) and infant birthweight].

Wu D et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2001

[STR polymorphisms in five Chinese ethnic groups(2)].

Li SB et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2000

[DNA polymorphisms and haplotypes in the apoAI-CIII gene region and coronary heart disease].

Meng X et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 1990

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."