Varaico: Literature-Extracted Genetic Variants

Gene:ABCC1
Variant:p.C43S
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ABCC1

NM_004996.4:p.C43S

Associated Papers

The influence of naturally occurring and in silico-informed mutations of MRP1/ABCC1 on the transport of arsenic triglutathione.

Li W et al.

Chemico-biological Interactions, 2026

Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers.

Li S et al.

Journal of Advanced Research, 2025

40436141 (PubMed )
Supplement: 1-s2.0-S2090123225003625-mmc2.xlsx › Table_S3

How Cryo-EM Has Expanded Our Understanding of Membrane Transporters.

Baril SA et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx ) with Knockout Capability.

Krohn M et al.

Molecular Pharmacology, 2019

Non-coding polymorphisms in nucleotide binding domain 1 in ABCC1 gene associate with transcript level and survival of patients with breast cancer.

Kunická T et al.

Plos One, 2014

Pharmacogenetics of membrane transporters: a review of current approaches.

Sissung TM et al.

Methods in Molecular Biology (clifton, N.j.), 2014

Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1.

Conseil G et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013

ABCC1 polymorphism Arg723Gln (2168G> A) is associated with lung cancer susceptibility in a Chinese population.

Yin JY et al.

Clinical and Experimental Pharmacology & Physiology, 2011

Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.

Wang LL et al.

Basic & Clinical Pharmacology & Toxicology, 2011

Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.

Silverton L et al.

Drug Metabolism and Drug Interactions, 2011

Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.

Isokpehi RD et al.

Bioinformatics and Biology Insights, 2010

20981267 (PubMed )
Supplement: BBI-4-supplementary.xls › SNPs3D_-_Substitutions_from_Cys

Pharmacogenetics of membrane transporters: an update on current approaches.

Sissung TM et al.

Molecular Biotechnology, 2010

Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population.

Yin JY et al.

Pharmacogenetics and Genomics, 2009

Pharmacogenetics of membrane transporters: a review of current approaches.

Sissung TM et al.

Methods in Molecular Biology (clifton, N.j.), 2008

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

Cascorbi I

Pharmacology & Therapeutics, 2006

Role of Cys-603 in dimer/oligomer formation of the breast cancer resistance protein BCRP/ABCG2.

Kage K et al.

Cancer Science, 2005

Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).

Létourneau IJ et al.

Pharmacogenetics and Genomics, 2005

Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.

Conseil G et al.

Pharmacogenetics and Genomics, 2005

Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).

Leslie EM et al.

Biochemistry, 2003

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects.

Ito S et al.

Pharmacogenetics, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."