Associated Papers
The influence of naturally occurring and in silico-informed mutations of MRP1/ABCC1 on the transport of arsenic triglutathione.
Li W et al.
Chemico-biological Interactions, 2026
Structural and functional implications of ABCC1 variants on clinical statin response.
Crispim Tropéia N et al.
Journal of Biomolecular Structure & Dynamics, 2025
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Activated leukocyte cell adhesion molecule/cluster of differentiation 166 rs10933819 (G>A) variant is associated with familial intracranial aneurysms.
Aitkulova A et al.
Biomedical Reports, 2022
Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia.
Dong W et al.
Journal of Lipid Research, 2022
The First Cytoplasmic Loop in the Core Structure of the ABCC1 (Multidrug Resistance Protein 1; MRP1) Transporter Contains Multiple Amino Acids Essential for Its Expression.
Conseil G et al.
International Journal of Molecular Sciences, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
Genetic Diversity in Drug Transporters: Impact in African Populations.
Rajman I et al.
Clinical and Translational Science, 2020
Germline variant burden in multidrug resistance transporters is a therapy-specific predictor of survival in breast cancer patients.
Xiao Q et al.
International Journal of Cancer, 2020
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.
Chen S et al.
Drug Metabolism Reviews, 2016
Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1-MRP1) in the Polish population.
Słomka M et al.
Bmc Genetics, 2015
How well do whole exome sequencing results correlate with medical findings? A study of 89 Mayo Clinic Biobank samples.
Middha S et al.
Frontiers in Genetics, 2015
Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1.
Conseil G et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013
The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal.
Jungsuwadee P et al.
Pharmacogenetics and Genomics, 2012
ABCC1 polymorphism Arg723Gln (2168G> A) is associated with lung cancer susceptibility in a Chinese population.
Yin JY et al.
Clinical and Experimental Pharmacology & Physiology, 2011
ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.
Pajic M et al.
Pharmacogenetics and Genomics, 2011
Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.
Wang LL et al.
Basic & Clinical Pharmacology & Toxicology, 2011
Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.
Silverton L et al.
Drug Metabolism and Drug Interactions, 2011
Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma.
Zhao J et al.
World Journal of Gastroenterology, 2010
ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts.
Siedlinski M et al.
Pharmacogenetics and Genomics, 2009
Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population.
Yin JY et al.
Pharmacogenetics and Genomics, 2009
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Ley TJ et al.
Nature, 2008
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
Cascorbi I
Pharmacology & Therapeutics, 2006
Nucleotide sequence analyses of the MRP1 gene in four populations suggest negative selection on its coding region.
Wang Z et al.
Bmc Genomics, 2006
The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology.
Cervenak J et al.
Cancer Letters, 2006
Insight in eukaryotic ABC transporter function by mutation analysis.
Frelet A et al.
Febs Letters, 2006
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity.
Wojnowski L et al.
Circulation, 2005
Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).
Létourneau IJ et al.
Pharmacogenetics and Genomics, 2005
Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.
Conseil G et al.
Pharmacogenetics and Genomics, 2005
Predicting drug response and toxicity based on gene polymorphisms.
Robert J et al.
Critical Reviews in Oncology/hematology, 2005
Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.
Mizuarai S et al.
International Journal of Cancer, 2004
Impact of genetic polymorphisms in transmembrane carrier-systems on drug and xenobiotic distribution.
Gerloff T
Naunyn-schmiedeberg's Archives of Pharmacology, 2004
A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance.
Conrad S et al.
Pharmacogenetics, 2002
Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.
Conrad S et al.
Journal of Human Genetics, 2001