Associated Papers
The influence of naturally occurring and in silico-informed mutations of MRP1/ABCC1 on the transport of arsenic triglutathione.
Li W et al.
Chemico-biological Interactions, 2026
Exome sequencing reveals new insights into the germline landscape of inflammatory breast cancer among Tunisian patients.
Boujemaa M et al.
Journal of Translational Medicine, 2025
The impact of CBR3 (rs1056892) and ABCC1 (rs45511401) genetic polymorphisms on doxorubicin-induced cardiotoxicity and the potential role of brain natriuretic peptide as an early cardiac biomarker in breast cancer patients.
El-Shorbagy EA et al.
Expert Opinion on Drug Metabolism & Toxicology, 2025
Silencing drug transporters in human primary muscle cells modulates atorvastatin pharmacokinetics: A pilot study.
Hoste E et al.
British Journal of Pharmacology, 2025
Structural and functional implications of ABCC1 variants on clinical statin response.
Crispim Tropéia N et al.
Journal of Biomolecular Structure & Dynamics, 2025
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability.
Dagli-Hernandez C et al.
Pharmacogenetics and Genomics, 2024
Association between genetic variants of transmembrane transporters and susceptibility to anthracycline-induced cardiotoxicity: Current understanding and existing evidence.
Ni MM et al.
Clinical Genetics, 2024
Atorvastatin-associated myotoxicity: A toxicokinetic review of pharmacogenetic associations to evaluate the feasibility of precision pharmacotherapy.
Hoste E et al.
Clinical Biochemistry, 2024
When the same treatment has different response: The role of pharmacogenomics in statin therapy.
Zheng E et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024
Genetic Polymorphisms in SLCO2B1 and ABCC1 Conjointly Modulate Atorvastatin Intracellular Accumulation in HEK293 Recombinant Cell Lines.
Hoste E et al.
Therapeutic Drug Monitoring, 2023
Genetic Testing in Evaluating Risk of Anthracycline Cardiomyopathy: Are We There Yet?
Wong-Siegel JR et al.
Jacc. Cardiooncology, 2023
Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy.
Bagdasaryan AA et al.
Cancers, 2022
Novel molecular biomarkers of cancer therapy-induced cardiotoxicity in adult population: a scoping review.
Cartas-Espinel I et al.
Esc Heart Failure, 2022
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.
Dagli-Hernandez C et al.
Pharmaceutics, 2022
Atorvastatin population pharmacokinetics in a real-life setting: Influence of genetic polymorphisms and association with clinical response.
Stillemans G et al.
Clinical and Translational Science, 2022
Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts.
Dagli-Hernandez C et al.
Pharmacological Reports : Pr, 2022
ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?
Bruckmueller H et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
Impact of variants in ATP-binding cassette transporters on breast cancer treatment.
Xiao Q et al.
Pharmacogenomics, 2020
Genetic factors in anthracycline-induced cardiotoxicity in patients treated for pediatric cancer.
Petrykey K et al.
Expert Opinion on Drug Metabolism & Toxicology, 2020
Germline variant burden in multidrug resistance transporters is a therapy-specific predictor of survival in breast cancer patients.
Xiao Q et al.
International Journal of Cancer, 2020
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
ATP-Binding Cassette Transporters in the Clinical Implementation of Pharmacogenetics.
López-Fernández LA
Journal of Personalized Medicine, 2018
In silico characterization of functional single nucleotide polymorphisms of folate pathway genes.
Vohra M et al.
Annals of Human Genetics, 2018
Association of ABCB1 (C3435T) and ABCC1 (G2012T) Polymorphisms with Clinical Response to Atorvastatin in Iranian Patients with Primary Hyperlipidemia.
Behdad N et al.
Iranian Biomedical Journal, 2017
Validating the pharmacogenomics of chemotherapy-induced cardiotoxicity: What is missing?
Magdy T et al.
Pharmacology & Therapeutics, 2016
Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.
Chen S et al.
Drug Metabolism Reviews, 2016
Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1-MRP1) in the Polish population.
Słomka M et al.
Bmc Genetics, 2015
Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine.
Simeon V et al.
International Journal of Molecular Sciences, 2015
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.
Witkiewicz AK et al.
Nature Communications, 2015
Clinical impact of ABCC1 and ABCC2 genotypes and haplotypes in mediating imatinib resistance among chronic myeloid leukaemia patients.
Au A et al.
Journal of Clinical Pharmacy and Therapeutics, 2014
Germline genetic variants in ABCB1, ABCC1 and ALDH1A1, and risk of hematological and gastrointestinal toxicities in a SWOG Phase III trial S0221 for breast cancer.
Yao S et al.
The Pharmacogenomics Journal, 2014
FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription.
Dhar SK et al.
Antioxidants & Redox Signaling, 2014
Non-coding polymorphisms in nucleotide binding domain 1 in ABCC1 gene associate with transcript level and survival of patients with breast cancer.
Kunická T et al.
Plos One, 2014
Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1.
Conseil G et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013
Genetic variability in the multidrug resistance associated protein-1 (ABCC1/MRP1) predicts hematological toxicity in breast cancer patients receiving (neo-)adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide (FEC).
Vulsteke C et al.
Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2013
Genetic association analysis of transporters identifies ABCC2 loci for seizure control in women with epilepsy on first-line antiepileptic drugs.
Grover S et al.
Pharmacogenetics and Genomics, 2012
The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal.
Jungsuwadee P et al.
Pharmacogenetics and Genomics, 2012
ABCC1 polymorphisms in anthracycline-induced cardiotoxicity in childhood acute lymphoblastic leukaemia.
Semsei AF et al.
Cell Biology International, 2012
Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application.
Yin J et al.
Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences, 2011
Pharmacogenomics of cardiovascular drugs and adverse effects in pediatrics.
Visscher H et al.
Journal of Cardiovascular Pharmacology, 2011
ABCC1 polymorphism Arg723Gln (2168G> A) is associated with lung cancer susceptibility in a Chinese population.
Yin JY et al.
Clinical and Experimental Pharmacology & Physiology, 2011
ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.
Pajic M et al.
Pharmacogenetics and Genomics, 2011
Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.
Steeghs N et al.
Investigational New Drugs, 2011
Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.
Wang LL et al.
Basic & Clinical Pharmacology & Toxicology, 2011
Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.
Silverton L et al.
Drug Metabolism and Drug Interactions, 2011
ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts.
Siedlinski M et al.
Pharmacogenetics and Genomics, 2009
Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population.
Yin JY et al.
Pharmacogenetics and Genomics, 2009