Associated Papers
SNP's use as a potential chemotoxicity stratification tool in breast cancer: from bench to clinic.
Moustafa HAM et al.
Functional & Integrative Genomics, 2025
Association Between ABCC2 -24C>T and Nab-Paclitaxel-induced Peripheral Neuropathy in Japanese Patients With Pancreatic Cancer.
Nakayama H et al.
Anticancer Research, 2024
Overexpression of P-glycoprotein and MRP-1 are pharmacogenomic biomarkers to determine steroid resistant phenotype in childhood idiopathic nephrotic syndrome.
Prasad N et al.
The Pharmacogenomics Journal, 2021
ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?
Bruckmueller H et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
Ethnogeographic and inter-individual variability of human ABC transporters.
Xiao Q et al.
Human Genetics, 2020
MDR1 Gene Polymorphisms and Its Association With Expression as a Clinical Relevance in Terms of Response to Chemotherapy and Prognosis in Ovarian Cancer.
Haque A et al.
Frontiers in Genetics, 2020
Polymorphisms of genes encoding drug transporters or cytochrome P450 enzymes and association with clinical response in cancer patients: a systematic review.
Kulma I et al.
Cancer Chemotherapy and Pharmacology, 2019
ABCB1 and CYP2D6 polymorphisms and treatment response of psychotic patients in a naturalistic setting.
Papazisis G et al.
Human Psychopharmacology, 2018
The molecular genetics of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis.
Cliff J et al.
Critical Reviews in Oncology/hematology, 2017
Genetic variation of CYP3A5 influences paclitaxel/carboplatin-induced toxicity in Chinese epithelial ovarian cancer patients.
Hu L et al.
Journal of Clinical Pharmacology, 2016
Are pharmacogenomic biomarkers an effective tool to predict taxane toxicity and outcome in breast cancer patients? Literature review.
De Iuliis F et al.
Cancer Chemotherapy and Pharmacology, 2015
MDR1 gene polymorphisms and P-glycoprotein expression in respiratory diseases.
Milojkovic M et al.
Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2015
Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.
Xiang C et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2015
Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: a systematic review and meta-analysis of observational studies.
Megías-Vericat JE et al.
The Pharmacogenomics Journal, 2015
Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment.
Pahnke J et al.
Neurobiology of Disease, 2014
Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib.
Beuselinck B et al.
Acta Oncologica (stockholm, Sweden), 2014
Resistance and intolerance to statins.
Reiner Z
Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd, 2014
ABCB1/MDR1 gene polymorphism and colorectal cancer risk: a meta-analysis of case-control studies.
He T et al.
Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 2013
Linkage disequilibrium between polymorphisms of ABCB1 and ABCC2 to predict the treatment outcome of Malaysians with complex partial seizures on treatment with carbamazepine mono-therapy at the Kuala Lumpur Hospital.
Subenthiran S et al.
Plos One, 2013
Interplay of pharmacogenetic variations in ABCB1 transporters and cytochrome P450 enzymes.
Yoo HD et al.
Archives of Pharmacal Research, 2011
Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.
Sai K et al.
Expert Opinion on Drug Metabolism & Toxicology, 2011
Lack of association between ABCB1 gene polymorphisms and pharmacoresistant epilepsy: an analysis in a western Chinese pediatric population.
Dong L et al.
Brain Research, 2011
ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.
Pajic M et al.
Pharmacogenetics and Genomics, 2011
Corpora amylacea deposition in the hippocampus of patients with mesial temporal lobe epilepsy: A new role for an old gene?
Das A et al.
Indian Journal of Human Genetics, 2011
Impact of CYP2C8*3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer.
Bergmann TK et al.
The Pharmacogenomics Journal, 2011
Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.
Wang LL et al.
Basic & Clinical Pharmacology & Toxicology, 2011
P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.
Cascorbi I
Handbook of Experimental Pharmacology, 2011
Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.
Silverton L et al.
Drug Metabolism and Drug Interactions, 2011
Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.
Buda G et al.
Annals of Hematology, 2010
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.
Grover S et al.
Biochimie, 2010
Emerging new technologies in Pharmacogenomics: rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).
Ishikawa T et al.
Pharmacology & Therapeutics, 2010
A phase II trial of triapine (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503.
Traynor AM et al.
Investigational New Drugs, 2010
Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations.
Benish RL et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2010
ABCB1: the role in Parkinson's disease and pharmacokinetics of antiparkinsonian drugs.
Vautier S et al.
Expert Opinion on Drug Metabolism & Toxicology, 2009
Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export.
Wang H et al.
Cancer, 2009
ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment.
Rebecchi IM et al.
Biochemical Pharmacology, 2009
The clinical impact of pharmacogenetics on the treatment of epilepsy.
Löscher W et al.
Epilepsia, 2009
Association of ABCB1 genetic variants with renal function in Africans and in Caucasians.
Bochud M et al.
Bmc Medical Genomics, 2008
Sequential influences of leukemia-specific and genetic factors on p-glycoprotein expression in blasts from 817 patients entered into the National Cancer Research Network acute myeloid leukemia 14 and 15 trials.
Seedhouse CH et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2007
Silent polymorphisms speak: how they affect pharmacogenomics and the treatment of cancer.
Sauna ZE et al.
Cancer Research, 2007
Pharmacogenetics of paclitaxel metabolism.
Spratlin J et al.
Critical Reviews in Oncology/hematology, 2007
Analyses of single nucleotide polymorphisms and haplotype linkage of the human ABCB1 (MDR1) gene in Korean.
Ryu HC et al.
Archives of Pharmacal Research, 2006
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
Cascorbi I
Pharmacology & Therapeutics, 2006
Implications of genetic polymorphisms in drug transporters for pharmacotherapy.
Kerb R
Cancer Letters, 2006
mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy.
Gréen H et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2006
Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.
Bosch TM et al.
Molecular Diagnosis & Therapy, 2006
Identification of polymorphisms on the MDR1 gene among Turkish population and their effects on multidrug resistance in acute leukemia patients.
Kaya P et al.
American Journal of Hematology, 2005
A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection.
Wang Z et al.
Human Molecular Genetics, 2005
Predicting drug response and toxicity based on gene polymorphisms.
Robert J et al.
Critical Reviews in Oncology/hematology, 2005
Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population.
Allabi AC et al.
European Journal of Clinical Pharmacology, 2005