Varaico: Literature-Extracted Genetic Variants

Gene:ABCC2
Variant:p.T153I
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ABCC2

NM_000392.5:p.T153I

Associated Papers

ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?

Bruckmueller H et al.

Expert Opinion on Drug Metabolism & Toxicology, 2021

Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics.

Heyes N et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018

Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.

Noguchi K et al.

Pharmacogenomics and Personalized Medicine, 2014

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.

Noguchi K et al.

Advanced Drug Delivery Reviews, 2009

The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein.

Yoshioka S et al.

Pharmaceutical Research, 2007

Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development.

Yanase K et al.

Cancer Letters, 2006

Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.

Mizuarai S et al.

International Journal of Cancer, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."