Associated Papers
Effects of ABC transporter polymorphism on the pharmacokinetics of pentoxifylline and its active metabolites in healthy Chinese subjects.
Guo L et al.
European Journal of Clinical Pharmacology, 2026
Single-nucleotide polymorphisms of donor CYP3A5 and recipient ABCB1 affect tacrolimus intrapatient variability in living donor liver transplantation: a retrospective cohort study.
Gongor SO et al.
Annals of Surgical Treatment and Research, 2025
Pharmacogenetics Approach for Personalized Tacrolimus Dosing in Heart Transplantation: A Case Report and Literature Review.
Nikpalj N et al.
Genes, 2025
Personalizing cancer therapy: the role of pharmacogenetics in overcoming drug resistance and toxicity.
Nafchi HM et al.
Molecular Biology Reports, 2025
Unravelling the genetic complexity of drug-resistant epilepsy: a critical narrative review.
Giacon M et al.
Expert Review of Clinical Pharmacology, 2025
ABCC2 as a novel covariate influencing oxcarbazepine pharmacokinetics in pediatric epilepsy: Insights from population modeling.
Shen X et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025
Effects of ABCG2 421C > A genetic polymorphism on the pharmacokinetics of rivaroxaban in healthy Chinese subjects.
Guo L et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2025
Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.
Shou W et al.
Bmc Genomics, 2025
Tramadol-related fatalities: Metabolic ratios & SNPs/INDELs belonging to UGT1A8, UGT2B7, ABCC2, and SLC22A1.
Aly SM et al.
Forensic Science International. Genetics, 2025
The Role of Candidate Polymorphisms in Drug Transporter Genes on High-Dose Methotrexate in the Consolidation Phase of the AIEOP-BFM ALL 2009 Protocol.
Braidotti S et al.
Clinical and Translational Science, 2025
The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.
Cacabelos R et al.
Expert Opinion on Drug Metabolism & Toxicology, 2025
Pharmacogenetics of Neoadjuvant MAP Chemotherapy in Localized Osteosarcoma: A Study Based on Data from the GEIS-33 Protocol.
Salazar J et al.
Pharmaceutics, 2024
Association of genetic variants in soy isoflavones metabolism-related genes with decreased lung cancer risk.
Xie D et al.
Gene, 2024
In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.
Kölz C et al.
British Journal of Pharmacology, 2024
Pharmacogenetic determinants of tenofovir diphosphate and lamivudine triphosphate concentrations in people with HIV/HBV coinfection.
Bae J et al.
Antimicrobial Agents and Chemotherapy, 2024
The reduced function allele SLCO1B1 c.521T>C is of no practical relevance for the renal graft function over the first post-transplant year in patients treated with mycophenolic acid.
Nađ Škegro S et al.
Pharmacogenetics and Genomics, 2024
Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.
Perini JA et al.
Toxics, 2024
Pharmacokinetic interactions between tacrolimus and Wuzhi capsule in liver transplant recipients: Genetic polymorphisms affect the drug interaction.
Huang S et al.
Chemico-biological Interactions, 2024
Atorvastatin-associated myotoxicity: A toxicokinetic review of pharmacogenetic associations to evaluate the feasibility of precision pharmacotherapy.
Hoste E et al.
Clinical Biochemistry, 2024
Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.
Zheng Y et al.
Frontiers in Pharmacology, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Case report: Acute liver failure during deferasirox therapy and the potential role of pharmacogenetics.
García-Fariña B et al.
Frontiers in Pharmacology, 2024
Retention of indoxyl sulfate in different genotypes of ABCC2 may explain variation in tacrolimus pharmacokinetics.
Wang J et al.
Peerj, 2024
Population pharmacokinetics of oxcarbazepine active metabolite in Chinese children with epilepsy.
Li X et al.
European Journal of Pediatrics, 2023
Single-nucleotide polymorphisms in ABC drug transporters alter expression and circulating tenofovir in healthy South African women exposed to pre-exposure prophylaxis.
Zondo NM et al.
Pharmacogenomics, 2023
Predictive Value of ABCC2 and UGT1A1 Polymorphisms on Irinotecan-Related Toxicities in Patients with Cancer.
Aoullay Z et al.
Genetic Testing and Molecular Biomarkers, 2023
Molecular and Clinical Links between Drug-Induced Cholestasis and Familial Intrahepatic Cholestasis.
Vitale G et al.
International Journal of Molecular Sciences, 2023
Association Between ABCG2, ABCB1, ABCC2 Efflux Transporter Single-Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real-Life Study.
Barnett-Griness O et al.
Clinical Pharmacology and Therapeutics, 2023
Blood ACE Phenotyping for Personalized Medicine: Revelation of Patients with Conformationally Altered ACE.
Danilov SM et al.
Biomedicines, 2023
Impact of ABCC2 1249G>A and -24C>T Polymorphisms on Lacosamide Efficacy and Plasma Concentrations in Uygur Pediatric Patients With Epilepsy in China.
Zhao T et al.
Therapeutic Drug Monitoring, 2023
Impact of single-nucleotide polymorphisms on tacrolimus pharmacokinetics in liver transplant patients after switching to once-daily dosing.
Park J et al.
Hepatology International, 2023
Loss of Function ABCG2 c.421C>A (rs2231142) Polymorphism Increases Steady-State Exposure to Mycophenolic Acid in Stable Renal Transplant Recipients: An Exploratory Matched Cohort Study.
Borić-Bilušić AA et al.
Advances in Therapy, 2023
Effects of splicing-regulatory polymorphisms in ABCC2, ABCG2, and ABCB1 on methotrexate exposure in Chinese children with acute lymphoblastic leukemia.
Li M et al.
Cancer Chemotherapy and Pharmacology, 2023
Pharmacogenetics of anxiety and depression in Alzheimer's disease.
Cacabelos R et al.
Pharmacogenomics, 2023
The Relationship of Uremic Toxin Indoxyl Sulfate and Intestinal Elimination Mechanisms in Hemodialysis Patients.
Tomášová A et al.
Kidney & Blood Pressure Research, 2023
Genetic polymorphisms influencing deferasirox pharmacokinetics, efficacy, and adverse drug reactions: a systematic review and meta-analysis.
Yampayon K et al.
Frontiers in Pharmacology, 2023
Genotype-Phenotype Association in ABCC2 Exon 18 Missense Mutation Leading to Dubin-Johnson Syndrome: A Case Report.
Kim JH et al.
International Journal of Molecular Sciences, 2022
Population-based meta-analysis and gene-set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids.
Handelman SK et al.
Hepatology Communications, 2022
Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.
Valentine H et al.
Cancer Research Communications, 2022
Rapid clearance of tacrolimus blood concentration triggered by variant pharmacogenes.
Šimičević L et al.
Journal of Clinical Pharmacy and Therapeutics, 2022
Use of Pharmacogenetics to Optimize Immunosuppressant Therapy in Kidney-Transplanted Patients.
Urzì Brancati V et al.
Biomedicines, 2022
Pharmacogenetic Analysis of Voriconazole Treatment in Children.
Tilen R et al.
Pharmaceutics, 2022
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.
Dagli-Hernandez C et al.
Pharmaceutics, 2022
Pharmacogenomics of soft tissue sarcomas: New horizons to understand efficacy and toxicity.
Gambale E et al.
Cancer Treatment and Research Communications, 2022
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Silgado-Guzmán DF et al.
Frontiers in Pharmacology, 2022
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Gong Y et al.
Journal of Clinical Pharmacy and Therapeutics, 2021
Association between pharmacokinetics of lenvatinib in healthy subjects and genetic polymorphisms of ABCB1 3435C>T and ABCB1 2677G>T/A.
Song H et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2021
Individualized Proteogenomics Reveals the Mutational Landscape of Melanoma Patients in Response to Immunotherapy.
Schmitt M et al.
Cancers, 2021
Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing.
Yoon JG et al.
Transplantation, 2021