Associated Papers
SNP's use as a potential chemotoxicity stratification tool in breast cancer: from bench to clinic.
Moustafa HAM et al.
Functional & Integrative Genomics, 2025
Association Between ABCC2 -24C>T and Nab-Paclitaxel-induced Peripheral Neuropathy in Japanese Patients With Pancreatic Cancer.
Nakayama H et al.
Anticancer Research, 2024
ADME gene polymorphisms do not influence the pharmacokinetics of docetaxel: Results from a population pharmacokinetic study in Indian cancer patients.
Patil A et al.
Cancer Medicine, 2021
ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?
Bruckmueller H et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
ABC transporter superfamily. An updated overview, relevance in cancer multidrug resistance and perspectives with personalized medicine.
Juan-Carlos PM et al.
Molecular Biology Reports, 2021
Clinical Relevance of ABCB1, ABCG2, and ABCC2 Gene Polymorphisms in Chronic Myeloid Leukemia Patients Treated With Nilotinib.
Loscocco F et al.
Frontiers in Oncology, 2021
Influences of ABC transporter and CYP3A4/5 genetic polymorphisms on the pharmacokinetics of lenvatinib in Chinese healthy subjects.
Li J et al.
European Journal of Clinical Pharmacology, 2020
ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.
Riera P et al.
Frontiers in Pharmacology, 2020
Application of pharmacogenetics in oncology.
Miteva-Marcheva NN et al.
Biomarker Research, 2020
Polymorphisms of genes encoding drug transporters or cytochrome P450 enzymes and association with clinical response in cancer patients: a systematic review.
Kulma I et al.
Cancer Chemotherapy and Pharmacology, 2019
Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.
Yee SW et al.
Clinical Pharmacology and Therapeutics, 2018
The molecular genetics of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis.
Cliff J et al.
Critical Reviews in Oncology/hematology, 2017
The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance Treatment.
Rudin S et al.
Genomics, Proteomics & Bioinformatics, 2017
Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.
Rodieux F et al.
Journal of Clinical Pharmacology, 2016
Genetic Variations of Drug Transporters Can Influence on Drug Response in Patients Treated with Docetaxel Chemotherapy.
Choi JR et al.
Cancer Research and Treatment, 2015
Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.
Xiang C et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2015
Polymorphisms in ATP-binding cassette transporter genes and interaction with diet and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study.
Kopp TI et al.
Scandinavian Journal of Gastroenterology, 2015
CYP3A5 and ABCB1 genotype influence tacrolimus and sirolimus pharmacokinetics in renal transplant recipients.
Li Y et al.
Springerplus, 2015
Genotype variability and haplotype profile of ABCB1 (MDR1) gene polymorphisms in Macedonian population.
Naumovska Z et al.
Prilozi (makedonska Akademija Na Naukite I Umetnostite. Oddelenie Za Medicinski Nauki), 2014
Linkage disequilibrium between polymorphisms of ABCB1 and ABCC2 to predict the treatment outcome of Malaysians with complex partial seizures on treatment with carbamazepine mono-therapy at the Kuala Lumpur Hospital.
Subenthiran S et al.
Plos One, 2013
ABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients.
Qu J et al.
Cns Neuroscience & Therapeutics, 2012
Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.
Lai Y et al.
Expert Opinion on Drug Metabolism & Toxicology, 2012
Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.
Sai K et al.
Expert Opinion on Drug Metabolism & Toxicology, 2011
The effects of CYP3A4, CYP3A5, ABCB1, ABCC2, ABCG2 and SLCO1B3 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of docetaxel in nasopharyngeal carcinoma patients.
Chew SC et al.
Cancer Chemotherapy and Pharmacology, 2011
P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.
Cascorbi I
Handbook of Experimental Pharmacology, 2011
Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.
Silverton L et al.
Drug Metabolism and Drug Interactions, 2011
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.
Grover S et al.
Biochimie, 2010
Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations.
Benish RL et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2010
The clinical impact of pharmacogenetics on the treatment of epilepsy.
Löscher W et al.
Epilepsia, 2009
Silent (synonymous) SNPs: should we care about them?
Hunt R et al.
Methods in Molecular Biology (clifton, N.j.), 2009
Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients.
Mosyagin I et al.
Epilepsia, 2008
MDR1 genotypes do not influence the absorption of a single oral dose of 600 mg valacyclovir in healthy Chinese Han ethnic males.
Zhang Y et al.
British Journal of Clinical Pharmacology, 2008
A drug transporter for all ages? ABCB1 and the developmental pharmacogenetics of cyclosporine.
Hesselink DA et al.
Pharmacogenomics, 2008
Sequential influences of leukemia-specific and genetic factors on p-glycoprotein expression in blasts from 817 patients entered into the National Cancer Research Network acute myeloid leukemia 14 and 15 trials.
Seedhouse CH et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2007
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.
Izzedine H et al.
The Journal of Infectious Diseases, 2006
Analyses of single nucleotide polymorphisms and haplotype linkage of the human ABCB1 (MDR1) gene in Korean.
Ryu HC et al.
Archives of Pharmacal Research, 2006
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
Cascorbi I
Pharmacology & Therapeutics, 2006
Implications of genetic polymorphisms in drug transporters for pharmacotherapy.
Kerb R
Cancer Letters, 2006
Single nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.
Dey S
Expert Opinion on Drug Delivery, 2006
Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.
Bosch TM et al.
Molecular Diagnosis & Therapy, 2006
MDR1 genotype do not influence the absorption of a single oral dose of 100 mg talinolol in healthy Chinese males.
Zhang WX et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 2005
Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies.
Jamroziak K et al.
Hematology (amsterdam, Netherlands), 2004
MDR1 haplotypes modify BEN disease risk: a study in Bulgarian patients with Balkan endemic nephropathy compared to healthy controls.
Atanasova S et al.
Nephron. Experimental Nephrology, 2004
The MDR1 (ABCB1) gene polymorphism and its clinical implications.
Ieiri I et al.
Clinical Pharmacokinetics, 2004
Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.
Lötsch J et al.
Clinical Pharmacokinetics, 2004
Genetic polymorphism at the 5' regulatory region of multidrug resistance 1 (MDR1) and its association with interindividual variation of expression level in the colon.
Taniguchi S et al.
Molecular Cancer Therapeutics, 2003
MDR1 genotype-related pharmacokinetics and pharmacodynamics.
Sakaeda T et al.
Biological & Pharmaceutical Bulletin, 2002
Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects.
Moriya Y et al.
Biological & Pharmaceutical Bulletin, 2002
Identification of NQO1 and GSTs genotype frequencies in Bulgarian patients with Balkan endemic nephropathy.
Toncheva DI et al.
Journal of Nephrology, 0