Varaico: Literature-Extracted Genetic Variants

Gene:ABCC2
Variant:p.G1086_D1087Splc
Back to variants list

ABCC2

NM_000392.5:p.G1086_D1087Splc

Associated Papers

Risk factors for abnormal hepatic enzyme elevation by methotrexate treatment in patients with rheumatoid arthritis: A hospital based-cohort study.

Hakamata J et al.

Modern Rheumatology, 2018

Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation.

Cecchin E et al.

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 2018

Effect of polymorphisms in transporter genes on dosing, efficacy and toxicity of maintenance therapy in children with acute lymphoblastic leukemia.

Gervasini G et al.

Gene, 2017

Polymorphisms and pharmacogenomics for the toxicity of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic review and meta-analysis.

Qiu Q et al.

Medicine, 2017

Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.

Chen S et al.

Drug Metabolism Reviews, 2016

Genetic polymorphisms of enzyme proteins and transporters related to methotrexate response and pharmacokinetics in a Japanese population.

Hashiguchi M et al.

Journal of Pharmaceutical Health Care and Sciences, 2016

Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate.

Stamp LK et al.

Pharmacogenetics and Genomics, 2010

Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

Ranganathan P et al.

The Journal of Rheumatology, 2008

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."