Associated Papers
Effects of ABC transporter polymorphism on the pharmacokinetics of pentoxifylline and its active metabolites in healthy Chinese subjects.
Guo L et al.
European Journal of Clinical Pharmacology, 2026
The impact of single nucleotide polymorphisms on the absorption, distribution, metabolism, and excretion of dietary (poly)phenols: a critical systematic review.
Tosi N et al.
Food & Function, 2025
Genome-wide screening of pharmacogenomic biomarkers in jordanian patients with genetic disorders.
Jarrar Y et al.
The Pharmacogenomics Journal, 2025
Single-nucleotide polymorphisms of donor CYP3A5 and recipient ABCB1 affect tacrolimus intrapatient variability in living donor liver transplantation: a retrospective cohort study.
Gongor SO et al.
Annals of Surgical Treatment and Research, 2025
Personalizing cancer therapy: the role of pharmacogenetics in overcoming drug resistance and toxicity.
Nafchi HM et al.
Molecular Biology Reports, 2025
Unravelling the genetic complexity of drug-resistant epilepsy: a critical narrative review.
Giacon M et al.
Expert Review of Clinical Pharmacology, 2025
Effects of ABCG2 421C > A genetic polymorphism on the pharmacokinetics of rivaroxaban in healthy Chinese subjects.
Guo L et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2025
Tramadol-related fatalities: Metabolic ratios & SNPs/INDELs belonging to UGT1A8, UGT2B7, ABCC2, and SLC22A1.
Aly SM et al.
Forensic Science International. Genetics, 2025
The Role of Candidate Polymorphisms in Drug Transporter Genes on High-Dose Methotrexate in the Consolidation Phase of the AIEOP-BFM ALL 2009 Protocol.
Braidotti S et al.
Clinical and Translational Science, 2025
The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.
Cacabelos R et al.
Expert Opinion on Drug Metabolism & Toxicology, 2025
A Systematic Review of SNPs Screening for Platinum-Related Pharmacodynamics and Pharmacokinetics Genes in Non-Small Cell Lung Cancer for Precision Medicine.
Afifah NN et al.
The Application of Clinical Genetics, 2025
Impacts of polymorphisms in drug-metabolizing enzyme and transporter genes on irinotecan toxicity and efficacy in Thai colorectal cancer patients.
Akarapredee N et al.
Plos One, 2025
Pharmacogenetics of Neoadjuvant MAP Chemotherapy in Localized Osteosarcoma: A Study Based on Data from the GEIS-33 Protocol.
Salazar J et al.
Pharmaceutics, 2024
In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.
Kölz C et al.
British Journal of Pharmacology, 2024
Effect of CYP3A5*3, ABCC2 C-24T, and ABCC2 C3972T Genetic Polymorphisms on Direct Cost of Kidney Transplant Recipients.
Choong CL et al.
Cureus, 2024
The Impact of ABCC2 -24C>T Gene Polymorphism on Graft Survival in Kidney Transplant Recipients.
Choong CL et al.
Journal of Personalized Medicine, 2024
Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.
Perini JA et al.
Toxics, 2024
Pharmacokinetic interactions between tacrolimus and Wuzhi capsule in liver transplant recipients: Genetic polymorphisms affect the drug interaction.
Huang S et al.
Chemico-biological Interactions, 2024
Atorvastatin-associated myotoxicity: A toxicokinetic review of pharmacogenetic associations to evaluate the feasibility of precision pharmacotherapy.
Hoste E et al.
Clinical Biochemistry, 2024
Intrahepatic Cholangiocarcinoma in Wilson's Disease: A Case Report.
Jang EJ et al.
The American Journal of Case Reports, 2024
Genetic polymorphisms as potential pharmacogenetic biomarkers for platinum-based chemotherapy in non-small cell lung cancer.
Sito H et al.
Molecular Biology Reports, 2024
Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.
Zheng Y et al.
Frontiers in Pharmacology, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Case report: Acute liver failure during deferasirox therapy and the potential role of pharmacogenetics.
García-Fariña B et al.
Frontiers in Pharmacology, 2024
Retention of indoxyl sulfate in different genotypes of ABCC2 may explain variation in tacrolimus pharmacokinetics.
Wang J et al.
Peerj, 2024
Risk-conferring HLA variants in an epilepsy cohort: benefits of multifaceted use of whole genome sequencing in clinical practice.
Vakrinou A et al.
Journal of Neurology, Neurosurgery, and Psychiatry, 2023
Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1.
de With M et al.
Clinical Pharmacokinetics, 2023
Predictive Value of ABCC2 and UGT1A1 Polymorphisms on Irinotecan-Related Toxicities in Patients with Cancer.
Aoullay Z et al.
Genetic Testing and Molecular Biomarkers, 2023
Molecular and Clinical Links between Drug-Induced Cholestasis and Familial Intrahepatic Cholestasis.
Vitale G et al.
International Journal of Molecular Sciences, 2023
Association Between ABCG2, ABCB1, ABCC2 Efflux Transporter Single-Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real-Life Study.
Barnett-Griness O et al.
Clinical Pharmacology and Therapeutics, 2023
Impact of single-nucleotide polymorphisms on tacrolimus pharmacokinetics in liver transplant patients after switching to once-daily dosing.
Park J et al.
Hepatology International, 2023
Polymorphisms Affecting the Response to Novel Antiepileptic Drugs.
Urzì Brancati V et al.
International Journal of Molecular Sciences, 2023
Pharmacogenetics of anxiety and depression in Alzheimer's disease.
Cacabelos R et al.
Pharmacogenomics, 2023
The Role of Single-Nucleotide Polymorphisms in Cholangiocarcinoma: A Systematic Review.
Wang G et al.
Cancers, 2022
Association of UGT1A1*6, UGT1A1*28, or ABCC2 c.3972C>T genetic polymorphisms with irinotecan-induced toxicity in Asian cancer patients: Meta-analysis.
Atasilp C et al.
Clinical and Translational Science, 2022
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Silgado-Guzmán DF et al.
Frontiers in Pharmacology, 2022
Case report: Two unique nonsense mutations in HTRA1-related cerebral small vessel disease in a Chinese population and literature review.
Chen W et al.
Frontiers in Neurology, 2022
Association between pharmacokinetics of lenvatinib in healthy subjects and genetic polymorphisms of ABCB1 3435C>T and ABCB1 2677G>T/A.
Song H et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2021
Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing.
Yoon JG et al.
Transplantation, 2021
Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.
Yip VLM et al.
British Journal of Clinical Pharmacology, 2021
Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.
van Eijk M et al.
The Pharmacogenomics Journal, 2021
ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?
Bruckmueller H et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters.
Iannaccone T et al.
Pharmaceuticals (basel, Switzerland), 2021
The association of transporter ABCC2 (MRP2) genetic variation and drug-induced hyperbilirubinemia.
Huang YS et al.
Journal of the Chinese Medical Association : Jcma, 2021
Racial Disparity in Drug Disposition in the Digestive Tract.
Gao S et al.
International Journal of Molecular Sciences, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
Impact of Pharmacogenetic Determinants of Tacrolimus and Mycophenolate on Adverse Events in Renal Transplant Patients.
Thishya K et al.
Current Drug Metabolism, 2021
The impact of cytochrome P450 3A genetic polymorphisms on tacrolimus pharmacokinetics in ulcerative colitis patients.
Furuse M et al.
Plos One, 2021
Clinical Relevance of ABCB1, ABCG2, and ABCC2 Gene Polymorphisms in Chronic Myeloid Leukemia Patients Treated With Nilotinib.
Loscocco F et al.
Frontiers in Oncology, 2021
Pharmacokinetics of Tenofovir Alafenamide Fumarate and Tenofovir in the Chinese People: Effects of Non-Genetic Factors and Genetic Variations.
Li X et al.
Pharmacogenomics and Personalized Medicine, 2021