Associated Papers
Proof-of-principle: nanopore adaptive sampling enables full blood group genome analysis and resolution of hybrid alleles.
Gueuning M et al.
Blood Advances, 2026
Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.
Shou W et al.
Bmc Genomics, 2025
Overcoming cancer drug-resistance calls for novel strategies targeting abnormal alternative splicing.
Zhang J et al.
Pharmacology & Therapeutics, 2024
APF2: an improved ensemble method for pharmacogenomic variant effect prediction.
Zhou Y et al.
The Pharmacogenomics Journal, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
In-vitro characterization of coding variants with predicted functional implications in the efflux transporter multidrug resistance protein 4 (MRP4, ABCC4).
Mailloux J et al.
Pharmacogenetics and Genomics, 2022
ABCC4, ITPA, NUDT15, TPMT and their interaction as genetic predictors of 6-mercaptopurine intolerance in chinese patients with acute lymphoblastic leukemia.
Fan POL et al.
Pediatric Hematology and Oncology, 2022
Optimizing thiopurine therapy in children with acute lymphoblastic leukemia: A promising "MINT" sequencing strategy and therapeutic "DNA-TG" monitoring.
Guo HL et al.
Frontiers in Pharmacology, 2022
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Gong Y et al.
Journal of Clinical Pharmacy and Therapeutics, 2021
Genetic landscape of 125 pharmacogenes in Chinese from the Chinese Millionome Database.
Qi G et al.
Scientific Reports, 2021
Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients.
Chamnanphon M et al.
Pharmacogenomics and Personalized Medicine, 2021
Pharmacogenetic Study of Trabectedin-Induced Severe Hepatotoxicity in Patients with Advanced Soft Tissue Sarcoma.
Maillard M et al.
Cancers, 2020
Donor-derived hypouricemia in irrelevant recipients caused by kidney transplantation.
Teng L et al.
Annals of Translational Medicine, 2020
Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation.
Azouzi S et al.
Blood, 2020
ErbB4 3'-UTR Variant (c.*3622A>G) is Associated with ER/PR Negativity and Advanced Breast Cancer.
Tabatabian M et al.
Indian Journal of Clinical Biochemistry : Ijcb, 2020
A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions.
Calderon-Ospina CA et al.
Pharmacogenomics and Personalized Medicine, 2020
A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance.
Tsukamoto M et al.
Cells, 2019
ATP-Binding Cassette Transporters in the Clinical Implementation of Pharmacogenetics.
López-Fernández LA
Journal of Personalized Medicine, 2018
Association of a potential functional mir-520f rs75598818 G>A polymorphism with breast cancer.
Meshkat M et al.
Journal of Genetics, 2018
Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4.
Tsukamoto M et al.
International Journal of Molecular Sciences, 2017
ABCC4 functional SNP in the 3' splice acceptor site of exon 8 (G912T) is associated with unfavorable clinical outcome in children with acute lymphoblastic leukemia.
Mesrian Tanha H et al.
Cancer Chemotherapy and Pharmacology, 2017
Clinical Applicability of Whole-Exome Sequencing Exemplified by a Study in Young Adults with the Advanced Cryptogenic Cholestatic Liver Diseases.
Kulecka M et al.
Gastroenterology Research and Practice, 2017
Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions.
Banerjee M et al.
Biochemical Pharmacology, 2016
Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.
Molnár J et al.
Plos One, 2016
Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma.
Goricar K et al.
Radiology and Oncology, 2014
Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.
Dulucq S et al.
Expert Opinion on Drug Metabolism & Toxicology, 2014
Systematic evaluation of genetic variants in three biological pathways on patient survival in low-stage non-small cell lung cancer.
Pankratz VS et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2011
Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia.
Ansari M et al.
Blood, 2009
Ethnic differences in drug metabolism and toxicity from chemotherapy.
Phan VH et al.
Expert Opinion on Drug Metabolism & Toxicology, 2009
The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.
Abla N et al.
The Journal of Pharmacology and Experimental Therapeutics, 2008
6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.
Janke D et al.
Human Mutation, 2008
Variability in human hepatic MRP4 expression: influence of cholestasis and genotype.
Gradhand U et al.
The Pharmacogenomics Journal, 2008
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.
Izzedine H et al.
The Journal of Infectious Diseases, 2006