Varaico: Literature-Extracted Genetic Variants

Gene:ABCC4
Variant:p.I174T
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ABCC4

NM_005845.5:p.I174T

Associated Papers

Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies.

Taylor ZL et al.

Cancers, 2021

Endogenous Metabolites-Mediated Communication Between OAT1/OAT3 and OATP1B1 May Explain the Association Between SLCO1B1 SNPs and Methotrexate Toxicity.

Martinez D et al.

Clinical Pharmacology and Therapeutics, 2018

Genetic and/or non-genetic causes for inter-individual and inter-cellular variability in transporter protein expression: implications for understanding drug efficacy and toxicity.

Koo SH et al.

Expert Opinion on Drug Metabolism & Toxicology, 2015

Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.

Dulucq S et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."