Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.P485A
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ABCG2

NM_004827.3:p.P485A

Associated Papers

The ABCG2/BCRP transporter and its variants - from structure to pathology.

Sarkadi B et al.

Febs Letters, 2020

Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets.

Cox MH et al.

The Biochemical Journal, 2018

Structure-function relationships in ABCG2: insights from molecular dynamics simulations and molecular docking studies.

Ferreira RJ et al.

Scientific Reports, 2017

Biochemical studies on the structure-function relationship of major drug transporters in the ATP-binding cassette family and solute carrier family.

Hong M

Advanced Drug Delivery Reviews, 2017

Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences.

Haider AJ et al.

Bioscience Reports, 2015

Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity.

Ni Z et al.

Biochemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."