Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.P480L
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ABCG2

NM_004827.3:p.P480L

Associated Papers

Understanding the impact of ABCG2 polymorphisms on drug pharmacokinetics: focus on rosuvastatin and allopurinol.

Kasten A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2024

In vitro identification of decreased function phenotype ABCG2 variants.

Suominen L et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2023

A Pan-Cancer Landscape of ABCG2 across Human Cancers: Friend or Foe?

Lyu C et al.

International Journal of Molecular Sciences, 2022

Using whole-genome sequencing to characterize clinically significant blood groups among healthy older Australians.

Jadhao S et al.

Blood Advances, 2022

35420653 (PubMed )
Supplement: mmc1.xlsx › Supplementary_table3

ABCG2/BCRP: variants, transporter interaction profile of substrates and inhibitors.

Safar Z et al.

Expert Opinion on Drug Metabolism & Toxicology, 2019

Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics.

Heyes N et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018

Transmembrane Domain Single-Nucleotide Polymorphisms Impair Expression and Transport Activity of ABC Transporter ABCG2.

Sjöstedt N et al.

Pharmaceutical Research, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."