Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.E446A
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ABCG2

NM_004827.3:p.E446A

Associated Papers

Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance.

Gose T et al.

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 2024

The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.

Khunweeraphong N et al.

Scientific Reports, 2017

Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study.

Li YF et al.

Journal of Molecular Graphics & Modelling, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."