Associated Papers
Effect of ABCG2 genetic polymorphisms on the transport of anti-seizure medications in hCMEC/D3 cell lines.
Bora S et al.
Cytotechnology, 2026
rs2231142 (421 C>A, Q141K) Is More Functionally Influential than rs2231137 (34 G>A, V12M) on Anticancer Drug Resistance Mediated by the ABCG2 Haplotype In Vitro.
Yamashita M et al.
International Journal of Molecular Sciences, 2025
The role of ABCG2 in health and disease: Linking cancer therapy resistance and other disorders.
El-Ashmawy NE et al.
Life Sciences, 2025
Impact of genetic polymorphisms of drug transporters ABCB1 and ABCG2 and regulators of xenobiotic transport and metabolism PXR and CAR on clinical efficacy of dasatinib in chronic myeloid leukemia.
Madejczyk AM et al.
Frontiers in Oncology, 2022
Multidrug efflux transporter ABCG2: expression and regulation.
Kukal S et al.
Cellular and Molecular Life Sciences : Cmls, 2021
Medically Important Alterations in Transport Function and Trafficking of ABCG2.
Homolya L
International Journal of Molecular Sciences, 2021
Identification of Specific Trafficking Defects of Naturally Occurring Variants of the Human ABCG2 Transporter.
Bartos Z et al.
Frontiers in Cell and Developmental Biology, 2021
The ABCG2/BCRP transporter and its variants - from structure to pathology.
Sarkadi B et al.
Febs Letters, 2020
Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics.
Heyes N et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018
Polymorphisms of ABCG2 and its impact on clinical relevance.
Zhang W et al.
Biochemical and Biophysical Research Communications, 2018
Rare ER protein misfolding-mistrafficking disorders: Therapeutic developments.
Hegde RN et al.
Tissue & Cell, 2017
Multiple common and rare variants of ABCG2 cause gout.
Higashino T et al.
Rmd Open, 2017
Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.
Chen S et al.
Drug Metabolism Reviews, 2016
Single-nucleotide polymorphisms of ABCG2 increase the efficacy of tyrosine kinase inhibitors in the K562 chronic myeloid leukemia cell line.
Skoglund K et al.
Pharmacogenetics and Genomics, 2014
Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.
Noguchi K et al.
Pharmacogenomics and Personalized Medicine, 2014
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.
Wang J et al.
Plos One, 2014
Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications.
Schnepf R et al.
Expert Opinion on Drug Metabolism & Toxicology, 2013
Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.
Nakanishi T et al.
Chinese Journal of Cancer, 2012
Ubiquitin-mediated proteasomal degradation of ABC transporters: a new aspect of genetic polymorphisms and clinical impacts.
Nakagawa H et al.
Journal of Pharmaceutical Sciences, 2011
Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.
Wang LL et al.
Basic & Clinical Pharmacology & Toxicology, 2011
Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-1.
Sugiyama T et al.
Biochemical and Biophysical Research Communications, 2011
Moving out: from sterol transport to drug resistance - the ABCG subfamily of efflux pumps.
Moitra K et al.
Drug Metabolism and Drug Interactions, 2011
BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization.
Shigeta J et al.
Cancer Science, 2010
Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system.
Wakabayashi-Nakao K et al.
Methods in Molecular Biology (clifton, N.j.), 2010
Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis.
Ishikawa T et al.
Advances in Pharmacological Sciences, 2010
Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2.
Nakagawa H et al.
The Febs Journal, 2009
Identification of compounds that correlate with ABCG2 transporter function in the National Cancer Institute Anticancer Drug Screen.
Deeken JF et al.
Molecular Pharmacology, 2009
Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations.
Furukawa T et al.
Pharmaceutical Research, 2009
Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.
Noguchi K et al.
Advanced Drug Delivery Reviews, 2009
Quality control of human ABCG2 protein in the endoplasmic reticulum: ubiquitination and proteasomal degradation.
Wakabayashi-Nakao K et al.
Advanced Drug Delivery Reviews, 2009
The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects.
Adkison KK et al.
British Journal of Clinical Pharmacology, 2008
Human ABC transporters ABCG2 (BCRP) and ABCG4.
Koshiba S et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008
Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2.
Nakagawa H et al.
The Biochemical Journal, 2008
The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein.
Yoshioka S et al.
Pharmaceutical Research, 2007
Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.
Tamura A et al.
Cancer Science, 2007
[Genetic polymorphisms of human ABC transporter ABCG2: Porphyria risk and ER quality control].
Wakabayashi K et al.
Seikagaku. the Journal of Japanese Biochemical Society, 2007
Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.
Tamura A et al.
Molecular Pharmacology, 2006
Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development.
Yanase K et al.
Cancer Letters, 2006
The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology.
Cervenak J et al.
Cancer Letters, 2006
Genetic polymorphisms of human ABC transporter ABCG2: development of the standard method for functional validation of SNPs by using the Flp recombinase system.
Tamura A et al.
Journal of Experimental Therapeutics & Oncology, 2006
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005