Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.G185V
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ABCG2

NM_004827.3:p.G185V

Associated Papers

Long-range communication between transmembrane- and nucleotide-binding domains does not depend on drug binding to mutant P-glycoprotein.

Bonito CA et al.

Journal of Biomolecular Structure & Dynamics, 2023

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.

Bruhn O et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.

Ozvegy-Laczka C et al.

Biochimica Et Biophysica Acta, 2005

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

Ishikawa T et al.

Biological & Pharmaceutical Bulletin, 2004

Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein.

Ruth A et al.

Biochemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."