Associated Papers
Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics.
Heyes N et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018
Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.
Noguchi K et al.
Pharmacogenomics and Personalized Medicine, 2014
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.
Wang J et al.
Plos One, 2014
Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.
Wang LL et al.
Basic & Clinical Pharmacology & Toxicology, 2011
Moving out: from sterol transport to drug resistance - the ABCG subfamily of efflux pumps.
Moitra K et al.
Drug Metabolism and Drug Interactions, 2011
Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis.
Ishikawa T et al.
Advances in Pharmacological Sciences, 2010
Identification of compounds that correlate with ABCG2 transporter function in the National Cancer Institute Anticancer Drug Screen.
Deeken JF et al.
Molecular Pharmacology, 2009
Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.
Noguchi K et al.
Advanced Drug Delivery Reviews, 2009
Human ABC transporters ABCG2 (BCRP) and ABCG4.
Koshiba S et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008
The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein.
Yoshioka S et al.
Pharmaceutical Research, 2007
Identification and functional assessment of BCRP polymorphisms in a Korean population.
Lee SS et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2007
Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.
Tamura A et al.
Molecular Pharmacology, 2006
Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development.
Yanase K et al.
Cancer Letters, 2006
The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology.
Cervenak J et al.
Cancer Letters, 2006
Genetic polymorphisms of human ABC transporter ABCG2: development of the standard method for functional validation of SNPs by using the Flp recombinase system.
Tamura A et al.
Journal of Experimental Therapeutics & Oncology, 2006
Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.
Sakurai A et al.
Expert Opinion on Pharmacotherapy, 2005
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005
Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N.
Vethanayagam RR et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2005
High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.
Ishikawa T et al.
Methods in Enzymology, 2005
Functional analysis of SNPs variants of BCRP/ABCG2.
Kondo C et al.
Pharmaceutical Research, 2004