Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.Q141*
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ABCG2

NM_004827.3:p.Q141*

Associated Papers

The Loss-of-Function ATP Binding Cassette Subfamily G Member 2 Polymorphism ABCG2 c.421C>A Reduces Lamotrigine Trough Concentrations in Adults with Epilepsy.

Božina N et al.

European Journal of Drug Metabolism and Pharmacokinetics, 2025

Breast cancer resistance protein polymorphism ABCG2 c.421C>A (rs2231142) moderates the effect of valproate on lamotrigine trough concentrations in adults with epilepsy.

Šušak Sporiš I et al.

Fundamental & Clinical Pharmacology, 2024

Association of ABCG2 Polymorphisms on Triple Negative Breast Cancer (TNBC) Susceptibility Risk.

Hao Ing Y et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

Bearing variant alleles at uridine glucuronosyltransferase polymorphisms UGT2B7 -161C > T (rs7668258) or UGT1A4*3 c.142 T > G (rs2011425) has no relevant consequences for lamotrigine troughs in adults with epilepsy.

Božina N et al.

European Journal of Clinical Pharmacology, 2023

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

Veerman GDM et al.

Eclinicalmedicine, 2023

Loss of Function ABCG2 c.421C>A (rs2231142) Polymorphism Increases Steady-State Exposure to Mycophenolic Acid in Stable Renal Transplant Recipients: An Exploratory Matched Cohort Study.

Borić-Bilušić AA et al.

Advances in Therapy, 2023

Racial Disparity in Drug Disposition in the Digestive Tract.

Gao S et al.

International Journal of Molecular Sciences, 2021

Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations.

Ronaldson PT et al.

Clinical Pharmacology and Therapeutics, 2016

Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.

Chen S et al.

Drug Metabolism Reviews, 2016

Association of ABCB1 and ABCG2 single nucleotide polymorphisms with clinical findings and response to chemotherapy treatments in Kurdish patients with breast cancer.

Ghafouri H et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.

Bruhn O et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?

Pang L et al.

Gastroenterology Research and Practice, 2014

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Lipid-lowing pharmacogenomics in Chinese patients.

Hu M et al.

Expert Review of Cardiovascular Therapy, 2013

Pharmacogenetics of membrane transporters: an update on current approaches.

Sissung TM et al.

Molecular Biotechnology, 2010

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.

Ieiri I et al.

Expert Opinion on Drug Metabolism & Toxicology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."