Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.Q141K
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ABCG2

NM_004827.3:p.Q141K

Associated Papers

Effect of ABCG2 genetic polymorphisms on the transport of anti-seizure medications in hCMEC/D3 cell lines.

Bora S et al.

Cytotechnology, 2026

Association of ABCG2 gene variants with urate levels in Mexican patients with type 2 diabetes and chronic kidney disease.

Mendoza-Carrera F et al.

Scientific Reports, 2026

Synergistic effects of ABCG2 Q141K variant in combination with alcohol consumption and male sex on gout risk in a rare-event Taiwanese cohort.

Lai ZL et al.

Scientific Reports, 2026

Intrinsic Factors Influencing Simvastatin and Simvastatin Acid Pharmacokinetics: Age-Related Studies in Thai Adults and Cross-Population Comparisons.

Srimatimanon T et al.

Clinical and Translational Science, 2026

Proteomic footprint of serum urate concentration and urate transporter ABCG2 dysfunctional polymorphism: a cross-sectional study.

Ohashi Y et al.

Rmd Open, 2026

Association between SLCO1B1, apolipoprotein E and ABCG2 genes and lipid response to rosuvastatin: a meta-analysis.

Li J et al.

Pharmacogenetics and Genomics, 2026

ATP-binding cassette transporter polymorphisms and the pharmacokinetics of oral esketamine.

Oude Nijhuis J et al.

Pharmacogenomics, 2026

Influence of pharmacokinetics-related polymorphisms on asciminib exposure in patients with Japanese chronic myeloid leukemia.

Takahashi N et al.

European Journal of Clinical Pharmacology, 2026

Effects of ABC transporter polymorphism on the pharmacokinetics of pentoxifylline and its active metabolites in healthy Chinese subjects.

Guo L et al.

European Journal of Clinical Pharmacology, 2026

Impact of SLCO1B1 Polymorphism and Vitamin D Status on Statin Efficacy and Tolerability in Postmenopausal Women.

Marušić R et al.

Biomedicines, 2026

Clinical Application of Pharmacogenomics in Stroke Management: Current Evidence and Future Directions.

Lee KJ et al.

Journal of Stroke, 2026

Genetic and epigenetic contribution of ABCG2 to gout susceptibility: a case-control study.

Clavijo-Cornejo D et al.

Molecular Biology Reports, 2025

Do genetic polymorphisms influence imatinib trough concentrations in patients with chronic myeloid leukemia? A systematic review and meta-analysis.

de Moraes FCA et al.

Expert Review of Anticancer Therapy, 2025

The impact of single nucleotide polymorphisms on the absorption, distribution, metabolism, and excretion of dietary (poly)phenols: a critical systematic review.

Tosi N et al.

Food & Function, 2025

Influence of genetic variants of imatinib on pharmacokinetics and recurrence-free survival in postoperative patients with gastrointestinal stromal tumor.

Sun L et al.

European Journal of Clinical Pharmacology, 2025

ABCB1 and ABCC10 polymorphisms predict sensitivity to first- and third-generation EGFR-TKIs in EGFR-mutant NSCLC.

Toda-Shiraga S et al.

Investigational New Drugs, 2025

Mechanism of Sodium-Glucose Cotransporter-2 Inhibitors for Uricosuria.

Bae E

Electrolyte & Blood Pressure : E & Bp, 2025

Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.

Twesigomwe D et al.

Scientific Reports, 2025

Influence of genetic polymorphisms on gefitinib pharmacokinetics and adverse drug reactions in non-small cell lung cancer patients.

Shenoy PV et al.

Cancer Metastasis Reviews, 2025

Effect of genetic polymorphism of rosuvastatin transporter gene rs2231137 on its clinical efficacy and safety.

Sharif M et al.

Scientific Reports, 2025

Association Between ABCG2 Polymorphism and Statin-Induced Adverse Events: A Meta-Analysis.

Lee DH et al.

Cardiovascular Toxicology, 2025

Influence of CYP2D6, CYP3A, and ABCG2 Genetic Polymorphisms on Ibrutinib Disposition in Chinese Healthy Subjects.

Fu K et al.

Pharmaceuticals (basel, Switzerland), 2025

Association of Functional Genetic Variations in Uric Acid Transporters with the Risk of Idiopathic Male Infertility: A Genetic Association Study and Bioinformatic Analysis.

Karimian M et al.

Biochemical Genetics, 2025

Association of the ABCG2 Q141K variant with gout in Kinh Vietnamese: a cross-sectional study.

Nguyen KP et al.

Clinical Rheumatology, 2025

Association of ABCG2 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.

Sharawi ZW et al.

Pharmaceuticals (basel, Switzerland), 2025

Single Nucleotide Variants of the SLC2A9 Gene Are Associated with Hyperuricemia in Mexican Patients with Type 2 Diabetes.

Vázquez-Rivera GE et al.

Archives of Medical Research, 2025

Relevance of selected pharmacogenetic polymorphisms to bleeding and thromboembolic risks in Chinese patients taking direct-acting oral anticoagulants.

Wang D et al.

British Journal of Clinical Pharmacology, 2025

Influence of pharmacokinetics-related gene polymorphisms on plasma levels of clozapine and its metabolites in Japanese patients with schizophrenia.

Kinoshita S et al.

Pcn Reports : Psychiatry and Clinical Neurosciences, 2025

Genetic Modulation of Silodosin Exposure and Efficacy: The Role of CYP3A4, CYP3A5, and UGT2B7 Polymorphisms in Benign Prostatic Hyperplasia Management.

Abdullaev SP et al.

Journal of Personalized Medicine, 2025

Personalizing cancer therapy: the role of pharmacogenetics in overcoming drug resistance and toxicity.

Nafchi HM et al.

Molecular Biology Reports, 2025

Clinical and Genetic Analysis of a Female Patient With Adolescent-Onset Gout.

Li X et al.

The Journal of Rheumatology, 2025

rs2231142 (421 C>A, Q141K) Is More Functionally Influential than rs2231137 (34 G>A, V12M) on Anticancer Drug Resistance Mediated by the ABCG2 Haplotype In Vitro.

Yamashita M et al.

International Journal of Molecular Sciences, 2025

Physiologically-based pharmacokinetic modeling of rosuvastatin in Chinese: Predicting the impact of SLCO1B1 and ABCG2 genetic variants and hepatic impairment on drug exposure.

Li L et al.

Journal of Pharmaceutical Sciences, 2025

Unveiling hidden risks: pharmacogenetic insights from a cross-sectional study of statin therapy in the Indian population.

Naushad SM et al.

Pharmacological Reports : Pr, 2025

Dolutegravir and Risk of Neuropsychiatric Adverse Events: A Pharmacogenetic Study.

De Greef J et al.

The Journal of Infectious Diseases, 2025

Pathogenic germline variants in small cell lung cancer: A systematic review and meta-analysis.

Ul Haq S et al.

Hgg Advances, 2025

40308030 (PubMed )
Supplement: mmc2.xlsx › Table_S3

Clinical impact of pharmacogenetic risk variants in a large chinese cohort.

Wei CY et al.

Nature Communications, 2025

40634300 (PubMed )
Supplement: 41467_2025_61644_MOESM1_ESM.pdf

Identification of pathogenic variants in the ABCG2 gene in patients with severe familial hyperuricemia and gout.

Toyoda Y et al.

Molecular and Cellular Biochemistry, 2025

Genetic background of selected hyperuricemia causing gout with pediatric onset.

Stiburkova B et al.

Joint Bone Spine, 2025

Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2).

Riselli AM et al.

Clinical Pharmacology and Therapeutics, 2025

Influence of Genetic Variation of GST, CYP, and ABC on the Safety and Efficacy of Cyclophosphamide-Based Therapy.

Yao ZW et al.

Clinical and Translational Science, 2025

Molecular Determinants of the Human Retinal Pigment Epithelium Cell Fate and Potential Pharmacogenomic Targets for Precision Medicine.

Zibetti C

International Journal of Molecular Sciences, 2025

40565279 (PubMed )
Supplement: ijms-26-05817-s001.zip › Table_S1_NGS_qc_and_WES_April2025_2_.xlsx › D2_hiPSCsvsPBMC_SNPs_InDels
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