Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.R137K
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ABCG2

NM_004827.3:p.R137K

Associated Papers

The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.

Khunweeraphong N et al.

Scientific Reports, 2017

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study.

Li YF et al.

Journal of Molecular Graphics & Modelling, 2007

Mutational analysis of ABCG2: role of the GXXXG motif.

Polgar O et al.

Biochemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."