Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.G51C
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ABCG2

NM_004827.3:p.G51C

Associated Papers

The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations.

Nagy T et al.

Cellular and Molecular Life Sciences : Cmls, 2021

32979053 (PubMed )
Supplement: 18_2020_3651_MOESM1_ESM.pdf

The ABCG2/BCRP transporter and its variants - from structure to pathology.

Sarkadi B et al.

Febs Letters, 2020

Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics.

Heyes N et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018

Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.

Noguchi K et al.

Pharmacogenomics and Personalized Medicine, 2014

Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis.

Ishikawa T et al.

Advances in Pharmacological Sciences, 2010

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.

Noguchi K et al.

Advanced Drug Delivery Reviews, 2009

Human ABC transporters ABCG2 (BCRP) and ABCG4.

Koshiba S et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008

The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein.

Yoshioka S et al.

Pharmaceutical Research, 2007

Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.

Tamura A et al.

Molecular Pharmacology, 2006

Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development.

Yanase K et al.

Cancer Letters, 2006

Genetic polymorphisms of human ABC transporter ABCG2: development of the standard method for functional validation of SNPs by using the Flp recombinase system.

Tamura A et al.

Journal of Experimental Therapeutics & Oncology, 2006

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.

Sakurai A et al.

Expert Opinion on Pharmacotherapy, 2005

High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.

Ishikawa T et al.

Methods in Enzymology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."