Varaico: Literature-Extracted Genetic Variants

Gene:ABCG2
Variant:p.V12M
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ABCG2

NM_004827.3:p.V12M

Associated Papers

Effects of ABC transporter polymorphism on the pharmacokinetics of pentoxifylline and its active metabolites in healthy Chinese subjects.

Guo L et al.

European Journal of Clinical Pharmacology, 2026

Influence of CYP2D6, CYP3A, and ABCG2 Genetic Polymorphisms on Ibrutinib Disposition in Chinese Healthy Subjects.

Fu K et al.

Pharmaceuticals (basel, Switzerland), 2025

Association of Functional Genetic Variations in Uric Acid Transporters with the Risk of Idiopathic Male Infertility: A Genetic Association Study and Bioinformatic Analysis.

Karimian M et al.

Biochemical Genetics, 2025

Association of ABCG2 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.

Sharawi ZW et al.

Pharmaceuticals (basel, Switzerland), 2025

rs2231142 (421 C>A, Q141K) Is More Functionally Influential than rs2231137 (34 G>A, V12M) on Anticancer Drug Resistance Mediated by the ABCG2 Haplotype In Vitro.

Yamashita M et al.

International Journal of Molecular Sciences, 2025

Pathogenic germline variants in small cell lung cancer: A systematic review and meta-analysis.

Ul Haq S et al.

Hgg Advances, 2025

40308030 (PubMed )
Supplement: mmc2.xlsx › Table_S3

Influence of Genetic Variation of GST, CYP, and ABC on the Safety and Efficacy of Cyclophosphamide-Based Therapy.

Yao ZW et al.

Clinical and Translational Science, 2025

Exploring the effect of intracellular loop 1 genetic variants in human ABCG2 on transport activity and protein abundance.

Sjöstedt N et al.

Drug Metabolism and Pharmacokinetics, 2025

Effects of ABCG2 421C > A genetic polymorphism on the pharmacokinetics of rivaroxaban in healthy Chinese subjects.

Guo L et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2025

Safety of teriflunomide in Chinese adult patients with relapsing multiple sclerosis: A phase IV, 24-week multicenter study.

Quan C et al.

Chinese Medical Journal, 2025

Variants of the ABCG2 gene in Mexican mestizo patients with prostate cancer.

Mimendi-Aguilar GM et al.

Cellular and Molecular Biology (noisy-le-grand, France), 2025

The role of ABCG2 in health and disease: Linking cancer therapy resistance and other disorders.

El-Ashmawy NE et al.

Life Sciences, 2025

Novel Genetic Loci in Early-Onset Gout Derived From Whole-Genome Sequencing of an Adolescent Gout Cohort.

Ji A et al.

Arthritis & Rheumatology (hoboken, N.j.), 2025

SLCO1B1 variants in a patient of African ancestry presenting with rosuvastatin-induced rhabdomyolysis: A case report.

Medwid S et al.

British Journal of Clinical Pharmacology, 2025

Impacts of polymorphisms in drug-metabolizing enzyme and transporter genes on irinotecan toxicity and efficacy in Thai colorectal cancer patients.

Akarapredee N et al.

Plos One, 2025

Discovery and prioritization of genetic determinants of kidney function in 297,355 individuals from Taiwan and Japan.

Chen HL et al.

Nature Communications, 2024

Genome-Wide Association Study of Atorvastatin Pharmacokinetics: Associations With SLCO1B1, UGT1A3, and LPP.

Mykkänen AJH et al.

Clinical Pharmacology and Therapeutics, 2024

Understanding the impact of ABCG2 polymorphisms on drug pharmacokinetics: focus on rosuvastatin and allopurinol.

Kasten A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2024

Genetic Variants in the ABCB1 and ABCG2 Gene Drug Transporters Involved in Gefitinib-Associated Adverse Reaction: A Systematic Review and Meta-Analysis.

Morau MV et al.

Genes, 2024

Placental efflux transporters and antiseizure or antidepressant medication use impact birth weight in MoBa cohort.

Hernandez MH et al.

Iscience, 2024

38455980 (PubMed )
Supplement: mmc1.pdf

ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.

Singh H et al.

Molecular Genetics & Genomic Medicine, 2024

Biochemical characterization of Jr(a-) blood type-related ABCG2 variants: Arg147Trp and Ser572Arg disrupt the plasma membrane localization of ABCG2.

Toyoda Y et al.

Transfusion, 2024

When the same treatment has different response: The role of pharmacogenomics in statin therapy.

Zheng E et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024

Examining the Association of Rare Allelic Variants in Urate Transporters SLC22A11, SLC22A13, and SLC17A1 with Hyperuricemia and Gout.

Vávra J et al.

Disease Markers, 2024

Case report: Avoiding intolerance to antipsychotics through a personalized treatment approach based on pharmacogenetics.

Korošec Hudnik L et al.

Frontiers in Psychiatry, 2024

Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.

Zheng Y et al.

Frontiers in Pharmacology, 2024

Association of ABCG2 Polymorphisms on Triple Negative Breast Cancer (TNBC) Susceptibility Risk.

Hao Ing Y et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

In vitro identification of decreased function phenotype ABCG2 variants.

Suominen L et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2023

Hemolytic disease of the newborn due to anti-Jra from a Chinese mother with one novel and one classic heterozygous mutation.

Xiao J et al.

Transfusion Medicine (oxford, England), 2023

Pharmacogenomics of response to statin treatment and susceptibility to statin-induced adverse drug reactions in Asians: a scoping review.

Yow HY et al.

Asian Biomedicine : Research, Reviews and News, 2023

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

Veerman GDM et al.

Eclinicalmedicine, 2023

Relationship Between Osimertinib Concentration and Clinical Response in Japanese Patients With Non-small Cell Lung Cancer.

Yamazaki M et al.

Anticancer Research, 2023

A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics.

Lehtisalo M et al.

British Journal of Clinical Pharmacology, 2023

The pharmacogenomic landscape of an Indigenous Australian population.

Samarasinghe SR et al.

Frontiers in Pharmacology, 2023

37284308 (PubMed )
Supplement: Table3.xlsx › HGMD-ClinVar_14_known_variants

Comparative analysis of MTP -493G/T and ABCG2 34G/A polymorphisms and theirs expression in HIV-associated lipodystrophy patients.

Singh H et al.

Frontiers in Cardiovascular Medicine, 2023

A meta-analysis and experimental data for multidrug resistance genes in breast cancer.

Zaib S et al.

African Health Sciences, 2022

Impact of Genetic Polymorphisms and Biomarkers on the Effectiveness and Toxicity of Treatment of Chronic Myeloid Leukemia and Acute Myeloid Leukemia.

Alarcón-Payer C et al.

Journal of Personalized Medicine, 2022

Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis.

Alves R et al.

International Journal of Molecular Sciences, 2022

36077209 (PubMed )
Supplement: ijms-23-09815-s001.zip › ijms-1852648-supplementary.pdf

Clinical implications of germline variations for treatment outcome and drug resistance for small molecule kinase inhibitors in patients with non-small cell lung cancer.

Heersche N et al.

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 2022

Role of Pharmacogenetics in the Treatment of Acute Myeloid Leukemia: Systematic Review and Future Perspectives.

Pinto-Merino Á et al.

Pharmaceutics, 2022

Pharmacogenetics of Drugs Used in the Treatment of Cancers.

Franczyk B et al.

Genes, 2022

An Updated Review of Genetic Associations With Severe Adverse Drug Reactions: Translation and Implementation of Pharmacogenomic Testing in Clinical Practice.

Wang CW et al.

Frontiers in Pharmacology, 2022

Prediction of various blood group systems using Korean whole-genome sequencing data.

Hyun J et al.

Plos One, 2022

1–50 of 305 papers
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."