Varaico: Literature-Extracted Genetic Variants

Gene:ABL1
Variant:p.K245E
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ABL1

NM_005157.6:p.K245E

Associated Papers

The silent players: Atypical BCR‑ABL isoforms as biomarkers and therapeutic hurdles in CML pathogenesis (Review).

Zhou X et al.

Oncology Reports, 2025

Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia: the importance of characterizing ABL1 mutations in cerebrospinal fluid.

Sanchez R et al.

Annals of Hematology, 2017

BCR-ABL1 compound mutations in tyrosine kinase inhibitor-resistant CML: frequency and clonal relationships.

Khorashad JS et al.

Blood, 2013

Associations between imatinib resistance conferring mutations and Philadelphia positive clonal cytogenetic evolution in CML.

Schnittger S et al.

Genes, Chromosomes & Cancer, 2010

Instability of BCR-ABL gene in primary and cultured chronic myeloid leukemia stem cells.

Jiang X et al.

Journal of the National Cancer Institute, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."