Varaico: Literature-Extracted Genetic Variants

Gene:ABRAXAS1
Variant:p.S404A
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ABRAXAS1

NM_139076.3:p.S404A

Associated Papers

Profiling BRCA1-BRCT interactions and their functional relevance at amino acid resolution.

Mangkusaputra V et al.

Nucleic Acids Research, 2025

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.

Wu Q et al.

Molecular Cell, 2016

26778126 (PubMed )
Supplement: mmc1.pdf

The BRCA1-interacting protein Abraxas is required for genomic stability and tumor suppression.

Castillo A et al.

Cell Reports, 2014

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

Wang B et al.

Science (new York, N.y.), 2007

17525340 (PubMed )
Supplement: wang.som.pdf
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