Varaico: Literature-Extracted Genetic Variants

Gene:ACE
Variant:p.A67V
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ACE

NM_000789.4:p.A67V

Associated Papers

Defining the mechanism of cross-reactivity for a SARS-CoV-2 Beta-elicited antibody toward omicron sub-lineages.

Ayres F et al.

Structure (london, England : 1993), 2026

ACE-Dependent Alzheimer's Disease: Circulating ACE Phenotypes in Heterozygous Carriers of Rare ACE Variants.

Mironenko IV et al.

International Journal of Molecular Sciences, 2025

41009662 (PubMed )
Supplement: ijms-26-09099-s001.zip › ijms-3824164-supplementary.pdf

Domain-Specific Impacts of Spike Protein Mutations on Infectivity and Antibody Escape in SARS-CoV-2 Omicron BA.1.

Kim TH et al.

Journal of Microbiology and Biotechnology, 2025

Effects of Angiotensin-I-Converting Enzyme (ACE) Mutations Associated with Alzheimer's Disease on Blood ACE Phenotype.

Kryukova OV et al.

Biomedicines, 2024

39457722 (PubMed )
Supplement: biomedicines-12-02410-s001.zip › biomedicines-3224268-supplementary.pdf

Genetic analysis of SARS-CoV-2 spike gene using Next Generation Sequencing from COVID-19 patients in Erbil/Iraq.

Ghareeb AA et al.

Cellular and Molecular Biology (noisy-le-grand, France), 2024

Carriers of Heterozygous Loss-of-Function ACE Mutations Are at Risk for Alzheimer's Disease.

Danilov SM et al.

Biomedicines, 2024

38255267 (PubMed )
Supplement: biomedicines-12-00162-s001.zip › biomedicines-2780808-Supplementary.pdf

Development and application of an RT‒PCR assay for the identification of the delta and omicron variants of SARS-COV-2.

Shipulin GA et al.

Heliyon, 2023

Mutations in the receptor-binding domain of human SARS CoV-2 spike protein increases its affinity to bind human ACE-2 receptor.

Naresh GKRS et al.

Journal of Biomolecular Structure & Dynamics, 2023

Insight into SARS-CoV-2 Omicron variant immune escape possibility and variant independent potential therapeutic opportunities.

Alam MS

Heliyon, 2023

Antibody-dependent cellular cytotoxicity against SARS-CoV-2 Omicron sub-lineages is reduced in convalescent sera regardless of infecting variant.

Richardson SI et al.

Cell Reports. Medicine, 2023

Atomistic insights into the binding of SARS-CoV-2 spike receptor binding domain with the human ACE2 receptor: The importance of residue 493.

Carter C et al.

Journal of Molecular Graphics & Modelling, 2023

36401897 (PubMed )
Supplement: mmc1.docx

Seasonal effects decouple SARS-CoV-2 haplotypes worldwide.

Tomaszewski T et al.

F1000research, 2023

Genomic surveillance of genes encoding the SARS-CoV-2 spike protein to monitor for emerging variants on Jeju Island, Republic of Korea.

Ha YR et al.

Frontiers in Microbiology, 2023

SARS-CoV-2 Omicron (BA.1 and BA.2) specific novel CD8+ and CD4+ T cell epitopes targeting spike protein.

Parn S et al.

Immunoinformatics (amsterdam, Netherlands), 2022

In Silico Protein Folding Prediction of COVID-19 Mutations and Variants.

Bhowmick S et al.

Biomolecules, 2022

36359015 (PubMed )
Supplement: biomolecules-12-01665-s001.zip › biomolecules-1969693-supplementary.pdf

Omicron (B.1.1.529) - A new heavily mutated variant: Mapped location and probable properties of its mutations with an emphasis on S-glycoprotein.

Chakraborty C et al.

International Journal of Biological Macromolecules, 2022

Determinants of Spike infectivity, processing, and neutralization in SARS-CoV-2 Omicron subvariants BA.1 and BA.2.

Pastorio C et al.

Cell Host & Microbe, 2022

35931073 (PubMed )
Supplement: mmc3.pdf

Potential linear B-cells epitope change to a helix structure in the spike of Omicron 21L or BA.2 predicts increased SARS-CoV-2 antibodies evasion.

Al-Zyoud W et al.

Virology, 2022

One Size Does Not Fit All: The Past, Present and Future of Cystic Fibrosis Causal Therapies.

Ensinck MM et al.

Cells, 2022

SARS-CoV-2 BA.1 variant is neutralized by vaccine booster-elicited serum but evades most convalescent serum and therapeutic antibodies.

Lusvarghi S et al.

Science Translational Medicine, 2022

Sequence analysis of the emerging SARS-CoV-2 variant Omicron in South Africa.

Wang L et al.

Journal of Medical Virology, 2022

Characterization of the novel SARS-CoV-2 Omicron (B.1.1.529) variant of concern and its global perspective.

Saxena SK et al.

Journal of Medical Virology, 2022

Waves and variants of SARS-CoV-2: understanding the causes and effect of the COVID-19 catastrophe.

Thakur V et al.

Infection, 2022

Omicron and Delta variant of SARS-CoV-2: A comparative computational study of spike protein.

Kumar S et al.

Journal of Medical Virology, 2022

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein.

Ghosh N et al.

International Immunopharmacology, 2022

Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions.

Bhattacharya M et al.

Geroscience, 2022

SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex.

Mannar D et al.

Science (new York, N.y.), 2022

Variants of SARS CoV-2: mutations, transmissibility, virulence, drug resistance, and antibody/vaccine sensitivity.

Prüβ BM

Frontiers in Bioscience (landmark Edition), 2022

Mutations in human SARS-CoV-2 spike proteins, potential drug binding and epitope sites for COVID-19 therapeutics development.

Guruprasad K

Current Research in Structural Biology, 2022

Equine Anti-SARS-CoV-2 Serum (ECIG) Binds to Mutated RBDs and N Proteins of Variants of Concern and Inhibits the Binding of RBDs to ACE-2 Receptor.

Andrade SA et al.

Frontiers in Immunology, 2022

Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy.

De Marco C et al.

Frontiers in Microbiology, 2022

Molecular and Serological Characterization of the SARS-CoV-2 Delta Variant in Bangladesh in 2021.

Ghosh AK et al.

Viruses, 2021

Local occurrence and fast spread of B.1.1.7 lineage: A glimpse into Friuli Venezia Giulia.

Mio C et al.

Plos One, 2021

Structural Analysis of the SARS-CoV-2 Omicron Variant Proteins.

Yang Q et al.

Research (washington, D.c.), 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."