Varaico: Literature-Extracted Genetic Variants

Gene:ACE
Variant:p.T716I
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ACE

NM_000789.4:p.T716I

Associated Papers

A tool for the cheap and rapid screening of SARS-CoV-2 variants of concern (VoCs) by Sanger sequencing.

Burgos G et al.

Microbiology Spectrum, 2023

Mutations in the receptor-binding domain of human SARS CoV-2 spike protein increases its affinity to bind human ACE-2 receptor.

Naresh GKRS et al.

Journal of Biomolecular Structure & Dynamics, 2023

In Silico Protein Folding Prediction of COVID-19 Mutations and Variants.

Bhowmick S et al.

Biomolecules, 2022

36359015 (PubMed )
Supplement: biomolecules-12-01665-s001.zip › biomolecules-1969693-supplementary.pdf

SARS-CoV-2 Variants, Current Vaccines and Therapeutic Implications for COVID-19.

Liang HY et al.

Vaccines, 2022

SARS-CoV-2 variants and spike mutations involved in second wave of COVID-19 pandemic in India.

Muttineni R et al.

Transboundary and Emerging Diseases, 2022

Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera.

Rathnasinghe R et al.

Nature Communications, 2022

Waves and variants of SARS-CoV-2: understanding the causes and effect of the COVID-19 catastrophe.

Thakur V et al.

Infection, 2022

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein.

Ghosh N et al.

International Immunopharmacology, 2022

Clinical Characteristics, Transmissibility, Pathogenicity, Susceptible Populations, and Re-infectivity of Prominent COVID-19 Variants.

Yang Z et al.

Aging and Disease, 2022

A Rapid and Consistent Method to Identify Four SARS-CoV-2 Variants during the First Half of 2021 by RT-PCR.

Fabiani M et al.

Vaccines, 2022

Molecular Epidemiology of SARS-CoV-2 in Tunisia (North Africa) through Several Successive Waves of COVID-19.

Chouikha A et al.

Viruses, 2022

A comprehensive overview of identified mutations in SARS CoV-2 spike glycoprotein among Iranian patients.

Eslami S et al.

Gene, 2022

Mutations in human SARS-CoV-2 spike proteins, potential drug binding and epitope sites for COVID-19 therapeutics development.

Guruprasad K

Current Research in Structural Biology, 2022

Role of COVID-19 Vaccines in SARS-CoV-2 Variants.

Zhou Z et al.

Frontiers in Immunology, 2022

Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy.

De Marco C et al.

Frontiers in Microbiology, 2022

Genomic landscape of alpha-variant of SARS-CoV-2 circulated in Pakistan.

Fiaz N et al.

Plos One, 2022

The alpha/B.1.1.7 SARS-CoV-2 variant exhibits significantly higher affinity for ACE-2 and requires lower inoculation doses to cause disease in K18-hACE2 mice.

Bayarri-Olmos R et al.

Elife, 2021

SARS-CoV-2 new variants: Characteristic features and impact on the efficacy of different vaccines.

Khan A et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2021

Structural modelling of SARS-CoV-2 alpha variant (B.1.1.7) suggests enhanced furin binding and infectivity.

Mohammad A et al.

Virus Research, 2021

Higher infectivity of the SARS-CoV-2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data.

Khan A et al.

Journal of Cellular Physiology, 2021

Mutations in the B.1.1.7 SARS-CoV-2 Spike Protein Reduce Receptor-Binding Affinity and Induce a Flexible Link to the Fusion Peptide.

Socher E et al.

Biomedicines, 2021

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.

Collier DA et al.

Nature, 2021

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.

Reynolds CJ et al.

Science (new York, N.y.), 2021

Impact of the N501Y substitution of SARS-CoV-2 Spike on neutralizing monoclonal antibodies targeting diverse epitopes.

Cheng L et al.

Virology Journal, 2021

The N501Y spike substitution enhances SARS-CoV-2 transmission.

Liu Y et al.

Biorxiv : the Preprint Server for Biology, 2021

VOC 202012/01 Variant Is Effectively Neutralized by Antibodies Produced by Patients Infected before Its Diffusion in Italy.

Rondinone V et al.

Viruses, 2021

Structural Consequences of Variation in SARS-CoV-2 B.1.1.7.

Ostrov DA

Journal of Cellular Immunology, 2021

Implications of the Novel Mutations in the SARS-CoV-2 Genome for Transmission, Disease Severity, and the Vaccine Development.

Akkiz H

Frontiers in Medicine, 2021

Evolution, correlation, structural impact and dynamics of emerging SARS-CoV-2 variants.

Spratt AN et al.

Computational and Structural Biotechnology Journal, 2021

Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates.

Schrörs B et al.

Plos One, 2021

Proliferation of SARS-CoV-2 B.1.1.7 Variant in Pakistan-A Short Surveillance Account.

Umair M et al.

Frontiers in Public Health, 0

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