Associated Papers
Alzheimer's disease-linked ACE variants increase ACE1 catalytic activity and production of angiotensin II.
Salvo MA et al.
The Journal of Biological Chemistry, 2026
ACE-Dependent Alzheimer's Disease: Circulating ACE Phenotypes in Heterozygous Carriers of Rare ACE Variants.
Mironenko IV et al.
International Journal of Molecular Sciences, 2025
Structural effect of the H992D/H418D mutation of angiotensin-converting enzyme in the Indian population: implications for health and disease.
Kulshreshtha A et al.
Journal of Biomolecular Structure & Dynamics, 2025
Effects of Angiotensin-I-Converting Enzyme (ACE) Mutations Associated with Alzheimer's Disease on Blood ACE Phenotype.
Kryukova OV et al.
Biomedicines, 2024
Carriers of Heterozygous Loss-of-Function ACE Mutations Are at Risk for Alzheimer's Disease.
Danilov SM et al.
Biomedicines, 2024
Effect of ACE mutations on blood ACE phenotype parameters.
Kryukova OV et al.
Plos One, 2024
Evaluating the association between genetically proxied ACE inhibition and dementias.
Nassan M et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2023
The effect of ACE2 receptor, IFN-γ, and TNF-α polymorphisms on the severity and prognosis of the disease in SARS-CoV-2 infection.
Esen SG et al.
Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research, 2023
Intervention of next-generation sequencing in diagnosis of Alzheimer's disease: challenges and future prospects.
Chandy T
Dementia & Neuropsychologia, 2023
Genetic profiles of familial late-onset Alzheimer's disease in China: The Shanghai FLOAD study.
Xie XY et al.
Genes & Diseases, 2022
In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure.
Udosen B et al.
Bmc Research Notes, 2021
Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Zhou Y et al.
Science Advances, 2021
Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme.
Popova IA et al.
Protein Science : a Publication of the Protein Society, 2021
Aβ-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
Cuddy LK et al.
Science Translational Medicine, 2020
Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease.
Blumenau S et al.
Scientific Reports, 2020
Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients.
Fichna JP et al.
Human Genomics, 2018
Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.
Sassi C et al.
Plos One, 2016
How well do whole exome sequencing results correlate with medical findings? A study of 89 Mayo Clinic Biobank samples.
Middha S et al.
Frontiers in Genetics, 2015
De Novo variants in the KMT2A (MLL) gene causing atypical Wiedemann-Steiner syndrome in two unrelated individuals identified by clinical exome sequencing.
Strom SP et al.
Bmc Medical Genetics, 2014
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009