Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.P734L
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ACE2

NM_001371415.1:p.P734L

Associated Papers

Genetic investigations on singleton school aged children reveal novel variants and new candidate genes for hearing loss.

Khan H et al.

Scientific Reports, 2024

39271758 (PubMed )
Supplement: 41598_2024_71407_MOESM1_ESM.xlsx › HPK7_hom

Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.

Rodriguez JA et al.

Chemico-biological Interactions, 2022

36336003 (PubMed )
Supplement: mmc1.pdf

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.

Suryamohan K et al.

Communications Biology, 2021

33846513 (PubMed )
Supplement: 42003_2021_2030_MOESM1_ESM.pdf

COVID-19: The Effect of Host Genetic Variations on Host-Virus Interactions.

Chakravarty S

Journal of Proteome Research, 2021

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).

Guo X et al.

Journal of Translational Medicine, 2020

32831104 (PubMed )
Supplement: 12967_2020_2486_MOESM1_ESM.xls › gnomAD_v2.1.1_ENSG00000130234_2

Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome.

Shikov AE et al.

Frontiers in Genetics, 2020

33133145 (PubMed )
Supplement: Data_Sheet_2.xlsx › Table_S7
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