Associated Papers
Comparative analysis of ACE2 mutations and their impact on SARS-CoV-2 susceptibility within diverse ethnic groups.
Shafique R et al.
Journal of Biomolecular Structure & Dynamics, 2026
The landscape of rare genetic variants in familial Waldenström macroglobulinemia.
Pemov A et al.
Blood Neoplasia, 2024
Human variation in the protein receptor ACE2 affects its binding affinity to SARS-CoV-2 in a variant-dependent manner.
Santos TM et al.
Journal of Biomolecular Structure & Dynamics, 2023
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.
Talebi T et al.
Genetics Research, 2023
Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
Rodriguez JA et al.
Chemico-biological Interactions, 2022
Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS-CoV-2 from 946 whole-exome sequencing data in the Turkish population.
Duman N et al.
Journal of Medical Virology, 2022
Characterization of ACE2 naturally occurring missense variants: impact on subcellular localization and trafficking.
Badawi S et al.
Human Genomics, 2022
Structural genetics of circulating variants affecting the SARS-CoV-2 spike/human ACE2 complex.
Ortuso F et al.
Journal of Biomolecular Structure & Dynamics, 2022
Human ACE2 Polymorphisms from Different Human Populations Modulate SARS-CoV-2 Infection.
Hu P et al.
Viruses, 2022
Systematic review of host genetic association with Covid-19 prognosis and susceptibility: What have we learned in 2020?
Ferreira de Araújo JL et al.
Reviews in Medical Virology, 2022
An overview of human proteins and genes involved in SARS-CoV-2 infection.
Jahanafrooz Z et al.
Gene, 2022
SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.
Vadgama N et al.
Frontiers in Genetics, 2022
GDF15 and ACE2 stratify COVID-19 patients according to severity while ACE2 mutations increase infection susceptibility.
Torrens-Mas M et al.
Frontiers in Cellular and Infection Microbiology, 2022
Hypotheses and facts for genetic factors related to severe COVID-19.
Kotsev SV et al.
World Journal of Virology, 2021
Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2.
Bhattacharjee MJ et al.
Molecular Biology and Evolution, 2021
Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs.
Badary OA
The Pharmacogenomics Journal, 2021
Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19.
Monticelli M et al.
European Journal of Medical Genetics, 2021
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
Suryamohan K et al.
Communications Biology, 2021
Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19.
Choudhary S et al.
Annals of Laboratory Medicine, 2021
Comprehensive in silico identification of impacts of ACE2 SNPs on COVID-19 susceptibility in different populations.
Paniri A et al.
Gene Reports, 2021
ACE2, TMPRSS2, and Furin variants and SARS-CoV-2 infection in Madrid, Spain.
Torre-Fuentes L et al.
Journal of Medical Virology, 2021
ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19.
Al-Mulla F et al.
Heliyon, 2021
Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro.
Hashizume M et al.
Viruses, 2021
Genetic variability in COVID-19-related genes in the Brazilian population.
Secolin R et al.
Human Genome Variation, 2021
Genetics Insight for COVID-19 Susceptibility and Severity: A Review.
Fricke-Galindo I et al.
Frontiers in Immunology, 2021
The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy.
Chen F et al.
Frontiers in Cellular and Infection Microbiology, 2021
ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population.
Benetti E et al.
European Journal of Human Genetics : Ejhg, 2020
Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2.
Mohammad A et al.
Life Sciences, 2020
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M et al.
Scientific Data, 2020
Analysis of ACE2 genetic variants in 131 Italian SARS-CoV-2-positive patients.
Novelli A et al.
Human Genomics, 2020
Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).
Guo X et al.
Journal of Translational Medicine, 2020
Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome.
Shikov AE et al.
Frontiers in Genetics, 2020
Variants in ACE2 and TMPRSS2 Genes Are Not Major Determinants of COVID-19 Severity in UK Biobank Subjects.
Curtis D
Human Heredity, 2020